Background: Exposure to ionizing radiation is inevitable. Using of low-level laser therapy (LLLT) stimulates tissue repair and reduces inflammation. The objective of the present study aimed at evaluating the therapeutic efficacy of Helium-Neon (He-Ne) laser in stimulating the reparative processes in the liver of mice after whole body gamma-irradiation (WBγ-I). Materials and Methods: Two hundred...

Quantum dots are new types of fluorescent materials for biological labeling. As a result, QDs toxicity study is an essential requirement for future clinical applications. Therefore, the cytotoxic CdSe:ZnS quantum dots effects on some organs in mice are presented in this study. In this work, 10, 20 and 40 mg/kg doses of CdSe:ZnS quantum dots were injected to 32 adult male mice. Structural and op...

MicroRNAs has been shown to regulate lipogenesis in liver. The aim of the present study was to investigate whether the effects of resveratrol (RSV) on lipogenesis is associated with the changes in the expression of two miRNAs (miR-107 and miR-10b) that regulate lipogenic pathways. 30 wild type C57BL/6j male mice were randomly fed three diets: a standard chow diet (ND), a high fat diet (HFD, 60%...

objective(s) there are some reports in recent years indicating that renal ischemia - reperfusion (ir) induces deleterious changes in remote organs such as liver. the aim of this study was to investigate whether leukocytes have a role on the induction of oxidative stress in liver after renal ir. materials and methods inbred mice in ir donor group were subjected to renal ir injury. in sham donor ...

Fipronil is a phenylpyrazole insecticide that widely used as pesticide and veterinary drug, although studies suggest it could be toxic to mammals. The objectives of this study were examine the pharmacokinetic profile fipronil in mice, dogs, cats, evaluate its effects on emotional cognitive behaviors dogs cats using data obtained from mice. assessment vivo kinetics was conducted mice dogs. We al...

Objective(s):To evaluate the effect of trinitroglycerin (TNG) as nitric oxide donor agent on serum copper (Cu) and zinc (Zn) levels and liver enzymes in BALB/c mice infected with Leishmania major (L. major) MRHO/IR/75/ER. Materials and Methods: Inbred female mice were divided into three groups: healthy group (uninfected naive mice), control group (infected with L. major), and test group (L. maj...

liver is a major organ of the body which can be exposed to various chemicals, drugs, and many other xenobiotics such as bromobenzene. bromobenzene must be converted to its active metabolites to produce liver and kidney toxicity. livergol is an herbal product which contains silymarin. the objective of this study was to find out the protective effect of livergol against liver toxicity induced by ...