The high-yielding synthesis and application of the first polymer supported reagent for the kinetic resolution (KR) of amines through enantioselective acetylation is described; this new supported chiral reagent allows the KR of primary amines with excellent selectivities at room temperature; moreover, this supported approach is highly efficient as the Merrifield-supported chiral scaffold can be ...

Dewar, J. M. Pillinger, S. Sheridan, I. P. Wright, E. K. Gibson, J. A. Merrifield, C. J. Howe, L. J. Waugh and C. T. Pillinger, Planetary & Space Sciences, The Open University, Walton Hall, Milton Keynes. MK7 6AA UK. ([email protected]), Astromaterials Research Office, NASA Johnson Space Center, Houston, TX 77058, USA, Fluid Gravity Engineering, 1 West Street, Emsworth, PO10 7DX, UK, RAL Spa...

Merrifield resin was converted to various dialkyl-trihydroxybenzaldehyde resins and then to different bound imine resins. Fluorescence spectroscopy was used to continuously monitor the intermediates performed on the resins. Using fluorescent label (dansyl chloride) information on the kinetics of the amine cleavage was obtained. This study demonstrated that direct measures of fluorescence intens...

On page 144 of (3], a (see Gutman[l]), formulated as follows:

Recently we reviewed the work of Nlels K. Jerne, C&ar Milstein, and Georges J.F. Kohler, who shared the 1984 Nobel Prize in medicine. 1 We also examined the work of Carlo Rubbia and Simon van der Meer, joint recipients of the physics prize, and that of R. Bruce Merrifield, who was awarded the chemistry prize.z In this essay we review the achievements of the prizewinners in economics and literat...