The present work aims to characterize and quantify the phenolic composition and to evaluate the antioxidant activity of Glycyrrhiza glabra L. (commonly known as licorice) rhizomes and roots. The antioxidant potential of its methanol/water extract could be related to flavones (mainly apigenin derivatives), flavanones (mainly liquiritin derivatives), a methylated isoflavone and a chalcone, identi...

Antioxidant activities of the different extracts (n-heptane, chloroform, methanol) from roots and aerial parts Scorzonera veratrifolia by maceration method, as well total phenolic flavonoid content were examined first time in this study. The findings revealed that methanol extract S. exhibited greater DPPH radical scavenging (IC50: 0.62±0.60 mg/mL) iron (III) reduction capacity (1.56±0.03 mM Fe...

Singapore grouper iridovirus (SGIV) is a serious pathogen that negatively impacts aquaculture. Because of its 90% fatality rate, effective medications control SGIV infection are urgently needed. Glycyrrhiza uralensis well-known medicinal plant contains active ingredients with antiviral, antibacterial, and other biological activities. In this study, we evaluated the application G. components aga...

This study provides the scientific basis for the anti-inflammatory effects of licorice extract in a t-BHP (tert-butyl hydrogen peroxide)-induced liver damage model and the effects of its ingredients, glycyrrhizic acid (GA), liquiritin (LQ) and liquiritigenin (LG), in a lipopolysaccharide (LPS)-stimulated microglial cell model. The GA, LQ and LG inhibited the LPS-stimulated elevation of pro-infl...


 Purpose: To screen quality markers of Jie-Geng decoction (JGD) through multiple analytical methods and integration network pharmacology HPLC-ELSD fingerprint.
 Methods: Network was used to the potential bioactive components JGD. Simultaneously, fingerprint combined with carried out for determination chemical compounds in Subsequently, identification variations JGD were established r...

Modifying effects of dietary exposure of seven naturally occurring products on the development of colonic aberrant crypt foci (ACF) induced by azoxymethane (AOM) were investigated in male F344 rats. The effects of these compounds on proliferation biomarkers such as the number of silver-stained nucleolar organizer region protein, ornithine decarboxylase activity, and polyamine concentration in t...