The isolation and characterization of two new arylnaphthalide lignans, jusmicranthin 1 and justirumalin 5, in addition to helioxanthin 4, taiwanin C 8, retrohelioxanthin 9 and justicidin A 10 from J. neesii, have been reported. Structure of 1 has been deduced as its ethyl and methyl ethers. Compound 1 is the first member .of angularly fused arylnaphthalide lignans having hydroxyl/alkoxyl group ...

Four new lignans, 3',4'-O,O-demethylenehinokinin (1), chamalignolide (2), 8'beta-hydroxyhinokinin (3) and 7beta,8beta-epoxyzuonin A (4), as well as (-)-hinokinin (5), and (-)-zuonin A (6), were isolated from the heartwood of Chamaecyparis obtusa var. formosana. The structures of these lignans were unambiguously determined by spectroscopic methods. And the absolute configuration of 1 was elucida...

Two new lignans, henricines A (1) and B (2), were isolated along with the eight known lignans, ganshisandrine (3), wulignan A(2) (4), epiwulignan A(1) (5), deoxyschisandrin (6), wulignan A(1) (7), epischisandrone (8), schisantherin A (9), and schisandrol A (10), from the stems of Schisandra henryi. The structures of the new compounds were elucidated based on the spectral analysis, including 1D ...

A series of lignans from Bupleurum salicifolium Soland (Umbelliferae) were tesled for nemalostatic activity on the cysts and freed secondstage juveniles of ¡he potalo cyst nematodes Globodera rostochiensis and G. pallida. None of Ihe six lignans lested-bursehemin, rnatairesinol, syringaresinol, Ihe novel produCI buplerol, guayarol. and a derivative, nortrachelogenin triacetale-showed nemalicida...

Dietary lignans are phyto-oestrogens that possibly influence human health. The present review deals with lignan bioavailability, the study of which is crucial to determine to what extent metabolism, absorption and excretion of lignans alter their biological properties. Since intestinal bacteria play a major role in lignan conversion, for instance by producing the enterolignans enterodiol and en...

The in vitro antiradical activity of Schisandra chinensis lignans was investigated using DPPH, ABTS+, Fenton reaction inhibition and tyrosine-nitration inhibition assays, as were the in vivo antidiabetic activities of selected lignans in an animal model of alloxan-induced diabetes. Different degrees of antiradical activity were found, depending upon the structural parameters of the tested compo...

Major lignans of sesame sesamin and sesamolin are benzodioxol--substituted furofurans. Sesamol, sesaminol, its epimers, episesamin transformation products found in processed products. Synthetic routes to all known but only sesamol is synthesized industrially. Biosynthesis furofuran begins with the dimerization coniferyl alcohol, followed by formation dioxoles, oxidation, glycosylation. Most gen...

Phaleria macrocarpa (Scheff.) Boerl., a member of the Thymelaeaceae, is traditionally used in Indonesia as medicinal plant against cancer. In this context, we isolated the lignans pinoresinol, lariciresinol and matairesinol from different parts of this plant. The enantiomeric composition of these lignans was determined by chiral column analysis. Pinoresinol and lariciresinol were mixtures of bo...

Twenty-one nonvitamin, nonmineral dietary supplements commonly consumed by women in Canada were analyzed for isoflavones (formononetin, daidzein, genistein, glycitein), lignans (pinoresinol, lariciresinol, secoisolariciresinol, matairesinol), and coumestrol to complement our previously published food phytoestrogen database. Supplements containing soy or red clover had the highest concentrations...