OBJECTIVE Examine response patterns to low-dose intravenous (IV) ketamine continuous infusions on multiple pain outcomes, and demonstrate effectiveness, safety, and tolerability of ketamine administration on general wards. DESIGN Retrospective case series of consecutive patients given low-dose IV ketamine continuous infusions. SETTING Walter Reed Army Medical Center, Washington, DC. PATIE...

BACKGROUND Gabapentin and ketamine are popular analgesic adjuvants for improving perioperative pain management. We designed this double-blind, placebo-controlled study to test and compare the preventive effects of perioperative ketamine and gabapentin on early and chronic pain after elective hysterectomy. METHODS Sixty patients undergoing abdominal hysterectomy were randomly assigned to 1 of ...

BACKGROUND The ideal anaesthetic technique for management of paediatric patients scheduled to undergo cardiac catheterisation is still not standardised. AIM To compare the effects of ketamine-propofol and ketamine-dexmedetomidine combinations on hemodynamic parameters and recovery time in paediatric patients undergoing minor procedures and cardiac catheterisation under sedation for various co...

objectives:the aim of the present study was to assess the analgesic efficacy of iv ketamine injection inaddition to nephrostomy tract infiltration of ketamine – bupivacaine on postoperative pain relief after tubeless percutaneous nephrolithotomy (pcnl). patients and methods: patients (n = 100), with renal stone who were candidates for pcnl were randomized to five groups with 20 cases in each: g...

PURPOSE The aim of this prospective, double-blind, randomized study was to investigate the analgesic effects of low-dose ketamine on intravenous patient-controlled analgesia (IV-PCA) with fentanyl for pain control in pediatric patients following the Nuss procedure for pectus excavatum. MATERIALS AND METHODS Sixty pediatric patients undergoing the Nuss procedure were randomly assigned to recei...

normal 0 false false false en-us x-none ar-sa background: in this randomized, double‑blinded study, we investigated the preemptive effects of propofol, remifentanil or ketamine on post‑operative pain scores and analgesic requirements in elective lower abdominal surgeries under general anesthesia during the first 24 h of post‑operative period. materials and methods: seventy five patients, ...

Total intravenous anesthesia (TIVA) can be an effective alternative to inhalational anesthesia. Various techniques of TIVA have been associated with significant cardiovascular alterations and prolonged wake up times. The purpose of this study was to determine if TIVA utilizing propofol, ketamine, and vecuronium would provide stable hemodynamics in normotensive ASA physical status I and II patie...

OBJECTIVES To observe the effects of both propofol/alfentanil and propofol/ketamine on sedation during upper gastrointestinal system endoscopy in morbidly obese patients (UGSEMOP). METHODS In a prospective, double-blinded, randomized clinical study, 52 patients scheduled for UGSEMOP were assigned to either group A (n=26; 10 µg/kg intravenous [IV] alfentanil) or group K (n=26; 0.5 mg/kg IV ket...

Introduction Ketamine is a phenylcyclohexylamine derivative comprising racemic mixture of S- and R-ketamine that possesses anesthetic, analgesic, anti-inflammatory, antidepressant activity. Oral (including extended release [PO]), intravenous (IV) sublingual (SL), transmucosal (TM), intranasal (IN), intramuscular (IM), rectal (PR), subcutaneous (SC) formulations have been developed since its com...

STUDY OBJECTIVE We investigate the effect of ondansetron on the incidence of vomiting in children who receive intravenous (IV) ketamine for procedural sedation and analgesia in the emergency department (ED). METHODS In this double-blind, randomized, placebo-controlled trial in a children's hospital ED, patients receiving IV ketamine (1 mg/kg) for ED procedures were randomized to receive eithe...