neospora caninum is an intracellular parasite which causes abortion in cattle worldwide. The aim of this study was to determine the seroprevalence of neospora caninum in cattle in the province of Kerman in South East Iran. Blood samples were collected from 285 cattle in the province of Kerman for determining the seroprevalence of neospora caninum. A total of 285 serum samples were tested for an...

Equine influenza (EI) is a major respiratory disease of horses, which is still causing substantial outbreaks worldwide despite several decades of surveillance and prevention. Alongside quarantine procedures, vaccination is widely used to prevent or limit spread of the disease. The panel of EI vaccines commercially available is probably one of the most varied, including whole inactivated virus v...

Saponins are used in medicine due to their pharmacological and immunological effects. To better understand interactions of saponins with model membranes and natural membranes of, for example, erythrocytes, Langmuir film balance experiments are well established. For most saponins, a strong interaction with cholesterol was demonstrated in dependence of both the aglycone part and the sugar moietie...

Background: Cationic immune stimulating complexes (PLUSCOMs) are particulate antigen delivery systems. PLUSCOMs consist of cationic immunostimulatory complexes (ISCOMs) derivatives and are able to elicit in vivo T cell responses against an antigen. Objective: To evaluate the effects of PLUSCOMs containing Leishmaniamajor antigens (SLA) on the type of immune response generated in the murine mod...

Rotavirus is a major cause of diarrhoea1 disease in young children and animals. Worldwide, it is responsible for 870,000 human deaths per year, primarily in the developing countries and causes significant economic losses in agriculture [ I ,2]. Natural infections in infancy prevent severe diarrhoea when subsequently challenged [3]. The current goal of rotavirus vaccination is to induce immunity...

New generation vaccines, based on isolated antigens, are safer than traditional ones, comprising the whole pathogen. However, major part of purified antigens has weak immunogenicity. Therefore, elaboration of new adjuvants, more effective and safe, is an urgent problem of vaccinology. Tubular immunostimulating complexes (TI-complexes) are a new type of nanoparticulate antigen delivery systems w...