R etinal vein occlusion (RVO) causes vision loss mostly because of the development of intraretinal leakage that leads to macular edema. The treatment of cystoid macular edema (CME) secondary to RVO has evolved considerably during the past decade. Anti-VEGF agents have become the standard of care for CME secondary to both branch (BRVO) and central retinal vein occlusion (CRVO). Because the under...

PURPOSE To report on the intraocular use of a steroid slow-release device in an attempt to avoid multiple intraocular triamcinolone injections in chronic sympathetic ophthalmia. METHODS A 47-year-old patient with sympathetic ophthalmia had received 17 intravitreal triamcinolone injections to suppress the uveitis, to increase intraocular pressure, and to reduce systemic anti-inflammatory medic...

Abstract: Title: Teratogenic Effects of Intravitreal Injection of Bevacizumab in Pregnant Rat Models Aim: To investigate teratogenic effect of intravitreal injection of bevacizumab in pregnant rat model Methods: Twenty seven female Wistar rat were inseminated. Pregnant rats were divided into 6 groups (three groups as case and three as control groups). Each case and control groups divided accord...

PURPOSE The incidence of infectious endophthalmitis associated with intravitreal injection (IVI) of steroid has been reported to be as high as 0.87%. This study was designed to investigate whether the antimicrobial activity of intravitreal methotrexate (MTX) alters the incidence or course of bacterial endophthalmitis associated with IVI in a rabbit model. METHODS A rabbit model of endophthalm...

Diabetic macular oedema is a major cause of severe visual loss whose pathogenesis appears to be complex and multifactorial. For many years laser photocoagulation has been the standard of care for the treatment of this condition. Emerging pharmacologic approaches are being evaluated through randomised controlled trials. Triamcinolone acetonide has been proposed as a promising option, due to its ...

Introduction: Diabetic macular edema (DME) is a debilitating complication of the diabetic eye. Vascular Endothelial Growth Factor (VEGF) was found to be responsible for this disease entity, and anti-VEGF remains main treatment DME. Inflammatory processes occur in eye, with some researchers postulates role them making This study’s objective search alternative using Non-Steroid Anti-Inflammatory ...

A 73-year-old woman underwent vitrectomy and intravitreal triamcinolone acetonide (IVTA) of the right eye and cataract surgery with IVTA of the left eye, for bilateral diabetic macular edema. The patient presented with visual loss in both eyes three-months postoperatively. The fundoscopic examination revealed white-yellow, necrotic peripheral lesions in the superotemporal quadrant of both eyes....

Abstract: Title: Teratogenic Effects of Intravitreal Injection of Bevacizumab in Pregnant Rat Models Aim: To investigate teratogenic effect of intravitreal injection of bevacizumab in pregnant rat model Methods: Twenty seven female Wistar rat were inseminated. Pregnant rats were divided into 6 groups (three groups as case and three as control groups). Each case and control groups divided accord...

PURPOSE To report the presenting features and clinical outcomes of a series of patients with noninfectious inflammation after intravitreal aflibercept injection. DESIGN Noncomparative consecutive case series. METHODS Medical records of patients who presented with noninfectious inflammation after intravitreal aflibercept injection between November 18, 2011 and June 30, 2013 were retrospectiv...

Seasonal hyperacute panuveitis (SHAPU), characterized by an unusual form of unilateral severe hyper acute diffused intraocular inflammation, is one of the mysterious eye diseases of which the definite cause and treatment remains yet to be tound out. In this study, a total of six cases were included. Aqueous and vitreous samples were subjected to direct microscopy and culture (bacterial or funga...