Abstract Gastric ulcer is a common health issue. Cotinus coggygria heartwood extracts rich in the flavonoids fustin and sulfuretin have shown protective effects rat model of indomethacin-induced gastric ulceration. Fustin itself has been ethanol-induced ulcer. In present study we aimed to reveal effect flavonoid isolated from was purified. The experiment performed on 30 male Wistar rats allocat...

This research investigated the effect of Andrographis paniculata (AP) on oxidative stress following indomethacin-induced gastric ulcer in rats. A total 20 male albino Wistar rats (150-180g) used for this study were grouped into four (n=5): 1, Negative Control; 2, Positive Control and 3, test group treated with normal chow, 20mg/kg indomethacin, mg/kg indomethacin plus omeprazole at AP 16.7 resp...

Purpose: To formulate and characterize indomethacin (IM) microspheres prepared with sugar cane wax microsperes. Methods: Microspheres were prepared by melt-emulsified dispersion and cooling-induced solidification method. The microspheres were characterized by scanning electron microscopy (SEM) and differntial scanning calorimetry (DSC) as well as for drug loading, and in vitro and in vivo relea...

Inhibition of tumor growth in a murine transplantable model of bladder cancer was attempted through manipulation of im mune response mechanisms by treatment of experimental an imals with indomethacm, a prostaglandin synthetase inhibitor, and/or polyinosinic:polycytidylic acid [poly(l:Q], an inducer of Interferon. Tumor-bearing animals and age-matched controls were inoculated i.p. with either ph...

background: the impact of positive intramammary lymph node (im ln) on the prognosis of patients with breast cancer has been debated for years; likewise, the standard management of patients with positive im ln remains unclear, especially when it is identified by preoperative imaging or by sentinel lymph node biopsy. the present study aims at reviewing the level of concurrent involvement of im ln...

The potential of liquisolid systems to improve the dissolution properties of a water-insoluble agent (indomethacin) was the purpose of this survey. In this study, different formulations of liquisolid tablets using different co-solvents (non-volatile solvents) were prepared and the effect of several amounts of them on the dissolution behaviour of indomethacin was investigated. It is worth mentio...

A crucial macroeconomic question facing the US economy is whether the value of the stock market has implications for consumption. If it does, it means that any severe downturn in the market could lead to a contraction of consumption, and therefore a contraction in the overall economy. The issue is one on which academics and the financial community seem to disagree. Rigorous academic works (Fama...

Chinese manufacturers, which produce nearly one-fourth of global manufacturing outputs, play important roles in the global supply chains for many products. The Chinese government proposed the “Made in China 2025” plan to help manufacturers upgrade their technology, so that the country will become a green and innovative “world manufacturing power”. It is important for researchers, practitioners,...

Indomethacin, an anti-inflammatory agent used for pain, fever and inflammation, causes severe lesions in the gastrointestinal tract humans animals. For this reason, there has been increase search new compounds that can help prevent and/or alleviate these caused by indomethacin. The aim of present study is to evaluate gastroprotective effect Juglans regia administration against indomethacin indu...

Objective: Determine the role of indomethacin on blood pressure lowering by captopril and losartan in hypertension patients. Study design: Randomized study design. Methodology: 200 patients with known problems including women men were treated this study. The complete protocol for was approved research center committee hospital. Patients randomly 50mg/day, 25mg two times/day. . Indomethacin 65 m...