There have been major developments in the treatment of psoriasis, an immune‐mediated skin disease, recent years, most notably with ‘biologic’ therapies that target components immune system. However, these agents do not cure disease and there are a few patients severe psoriasis who fail to respond any treatments currently available. Cell therapy has used successfully other conditions such as mul...

Multiple sclerosis (MS) is a complex disease which is correlated with increasing inflammatory factors, demyelination and axonal loss. In this auto-immune disease, Neuroinflammation is mediated by different types of T cells with macrophage/microglial activation and B cells involvement that interact in a collaborative manner. Focal inflammation is the main cause for the onset of relapses and coul...

anemia is the most common hematologic disorder in patients with ulcerative colitis (uc). in some cases, normochromic anemia results from the presence of chronic disease; however blood loss or malabsorption may lead to an iron deficiency anemia with hypochromic appearance. other rare hematologic manifestations associated with uc include myelodysplastic syndromes and leukemia. several investigato...

various commercial vaccines for immunization of broiler chickens against infectious bursal disease (ibd) are available, so it would be appropriate to compare the pathogenicity and immune response of chickens to these vaccines. in this study the pathogenicity and serologic response of four ibd vaccines, cloned d78®, bursine-2®, bursimune® and cevac gambo-l®, were evaluated in specific pathogen f...

celiac disease (cd) is an immune-mediated disorder resulting in nutrient malabsorption now thought to have a prevalence of 1:100 in the iranian population.symptoms of cd are included diarrhea, abdominal pain, steatorrhea, bloating, cramps, flatulence, weight loss, weakness and short stature. in addition to presenting symptoms, patients are also at increased risk of metabolic bone disease, lymph...