Clinical Images A 21-year-old man presented with symptoms of fatigue that had been progressing for several months. The patient had a history of depression and childhood constipation. Physical examination revealed conjunctival pallor, abdominal distention, and left upper quadrant firmness. Laboratory tests were positive for fecal occult blood test and revealed a serum hemoglobin level of 0.0048 ...

introduction: constipation is one of the most common pediatric disorders.in many cases, there is no anatomic endocrineor metabolic cause in explanation of chronic constipation.more than 85% of them called functional or idiopathic.constipation is one of the serious disease in iranian traditional medicine. besides the problem it causes, chronic constipation can be the origin of many disease. that...

colon transit time study with radio opaque markers is a simple method for assessment of colon motility disorder in patients with chronic idiopathic constipation. appendicitis caused by metallic objects has been reported repeatedly and is very important because of its complications. we report a case of acute appendicitis that was induced by impaction of radio opaque markers after colon transit t...

Fifteen women with intractable chronic idiopathic constipation dating from adolescence were investigated by anorectal manometry, neurophysiological evaluation of the conus medullaris and external anal sphincter. Comparison was made with 25 asymptomatic female control subjects. Urological disturbances were common amongst the constipated, in five of whom incidental lumbosacral spinal dysraphism w...

Inflammation of the myenteric plexus of the gastrointestinal tract is a very rare pathological condition, with few reports in the medical literature. This pathological condition causes atonic gut motor dysfunction and is principally secondary to other diseases, being reported nearly solely as a paraneoplastic phenomenon in neuroendocrine lung tumors, including small cell carcinomas or neuroblas...

BACKGROUND Clinical trials of several new treatments for opioid-induced constipation (OIC), chronic idiopathic constipation (CIC) and constipation-predominant irritable bowel syndrome (IBS-C) have focused on differences between subjects relieved of constipation with placebo and active treatment. Patients and clinicians however, are more interested in the probability these treatments provide act...

BACKGROUND It has been suggested that slow transit constipation (STC) may be part of a panenteric motor disorder. AIM To evaluate motility of an upper gastrointestinal organ, the gall bladder, in 16 patients with STC and 20 healthy controls. METHODS Gall bladder emptying (ultrasonography) was studied in response to neural, cephalic-vagal stimulation with modified sham feeding (MSF) for 90 m...

Severe idiopathic constipation affects predominantly young women. We have evaluated the results of colectomy in 44 women with a normal diameter colon and with a median bowel frequency of once per four weeks. The operations were done in one hospital over a 15 year period. After operation 22 patients had normal bowel frequency, 17 diarrhoea (greater than three bowel actions/day), and five persist...