Ten subjects received secretin and cholecystokinin or, in duplicate tests, the two hormones together with either diazepam or diazepam plus hyoscine butylbromide in order to determine whether these drugs, which are often used during retrograde endoscopic cannulation of the pancreatic duct, affect pancreatic and biliary secretion in response to the hormones. Diazepam with hyoscine butylbromide re...

Using G.29.505 the incidence of excitatory phenomena occurring after premedication with atropine and opiate was insignificantly different from that after atropine alone, whereas after hyoscine it was three times as high. Respiratory disturbances were significantly less frequent when an opiate was used with atropine than after atropine or hyoscine alone. G.29.505 was compared with nitrous oxide ...

purpose: oculocardiac reflex (ocr) is a frequent event during strabismus surgery. the aim of this study is to compare the preventive effect of intravenous lidocaine and hyoscine on ocr.methods: this prospective, randomized clinical trial was performed on 75 patients (5-63 years old) underwent strabismus surgery. patients divided randomly into three groups. intravenous hyoscine (0.2 mg/kg), lido...

As a g roup these a lka lo ids exer t t w o qui te s e p a r a t e effects on m a m m a l s exposed to t h e m — an an t i cho l ine rg ic effect, a n d a c e n t r a l ne rvous s y s t e m d e p r e s s a n t effect. This combina t ion of p roper t ies , t he i r po t en t effects w i t h very sma l l dosage, a n d the i r w i d e s p r e a d d i s t r ibu t ion h a s m a d e t h e m f a m o u...

BACKGROUND AND STUDY AIMS Antispasmodics may improve mucosal visualization during colonoscope withdrawal, potentially improving polyp and adenoma detection. Meta-analysis and case-control studies suggest a 9 % to 13 % relative increase in adenoma and polyp detection. We aimed to assess the impact of hyoscine butylbromide on the expected visualization during colonoscope withdrawal using a CT col...

Mefenamic acid 500 mg orally was administered to nine healthy volunteers on four occasions 7 days apart. On two occasions allocated at random, activated charcoal (2.5 g of medicoal) was administered 1 h after the drug. Hyoscine butylbromide (20 mg intramuscularly) was given immediately after mefenamic acid on one of these occasions, and on one occasion after mefenamic acid without charcoal. Hyo...