BACKGROUND Idiopathic pulmonary fibrosis (IPF) is a rare and serious disease characterized by progressive lung-function loss. Limited evidence has been published on the impact of lung-function loss on subsequent patient outcomes. This study examined change in forced vital capacity (FVC) across IPF patients in the 6 months after diagnosis and its association with clinical and healthcare resource...

INTRODUCTION Chronic urticaria (CU), a proxy for chronic spontaneous urticaria, has been associated with a negative impact on health-related quality of life (HRQoL) and costs, but there is limited evidence on the burden of CU in Brazil. The objective of this study was to estimate the prevalence of CU and assess the burden of CU on HRQoL and healthcare resource utilization (HRU) among adults in ...

INTRODUCTION The prevalence of endometriosis and the need for treatment in the USA has led to the need to explore the contemporary cost burden associated with the disease. This retrospective cohort study compared direct and indirect healthcare costs in patients with endometriosis to a control group without endometriosis. METHODS Women aged 18-49 years with endometriosis (date of initial diagn...

INTRODUCTION A retrospective study was conducted to assess the occurrence of blood donations that were ineligible due to Chagas disease infection from 1995 to 2009 at the Uberaba Regional Blood Center (HRU), Brazil, verify the tendency of this ineligibility, and describe the epidemiologic profile of the donors. METHODS Retrospective studies of serological ineligibility due to Chagas disease, ...

Specifically, suppose we have a BLP model which consists Currently most computer security models are classified among the tl:l~ types; access control, information flow, and non-interference. Within the realm of access control lies the classical Bell-LaPadula model. A BLP model consists of a set of subjects and objects, thr~e security level functions, and a discretionary access matrix together w...

Road extraction from high-resolution satellite images has become a significant focus in the field of remote sensing image analysis. However, factors such as shadow occlusion and spectral confusion hinder accuracy consistency road images. To overcome these challenges, this paper presents multi-scale fusion-based framework, HRU-Net, which exploits various scales resolutions features generated dur...

Abstract In the region of karst, there are valley areas that used by community as agricultural land. However, drought phenomena often occur in this area, so it is necessary to know presence water support processes. The aim research predict flow rates several systems using Soil and Water Assessment Tools (SWAT). SWAT was chosen because can simulate model with easy-to-obtain data. Required data s...

An efficient process for obtaining isoidide by catalytic epimerization of isosorbide using HRu(CO)Cl(PPh3)3/Xantphos (1/1) as organometallic catalyst without hydrogen is reported. The led to a thermodynamic equilibrium mixture containing 37% isosorbide, 57% and 6% isomannide in 1 h at 170 °C tert-amyl alcohol. same proportions were reached the precursor HRu(CO)Cl(PPh3)3 associated with sulfonat...

This randomised, double-blind, parallel-group, 1-yr study compared the effect of tiotropium 18 microg once daily (n=500) and placebo (n=510) on exacerbations, associated health resource use (HRU) and airflow limitation in chronic obstructive pulmonary disease (COPD) patients. The mean+/-sd number of exacerbations during the past year was 2.14+/-1.40, the mean weekly morning peak expiratory flow...