نتایج جستجو برای: hepatotoxic
تعداد نتایج: 1645 فیلتر نتایج به سال:
A 33 year old woman developed a florid form of chronic active hepatitis after exposure to halothane. Histological and immunological data suggested that autoimmune type chronic active hepatitis antedated the acute hepatotoxic sequelae of the hatothane anaesthesia. Studies on the immuno regulatory functions of peripheral blood lymphocytes revealed a marked defect in suppressor cell function. It i...
Herein we describe the synthesis and in vitro biological evaluation of thirteen new, racemic, diversely functionalized imidazo pyranotacrines as non-hepatotoxic, multipotent tacrine analogues. Among these compounds, 1-(5-amino-2-methyl-4-(1-methyl-1H-imidazol-2-yl)-6,7,8,9-tetrahydro-4H-pyrano[2,3-b]quinolin-3-yl)ethan-1-one (4) is non-hepatotoxic (cell viability assay on HepG2 cells), a select...
Liver being vulnerable to exogenous substances makes disease associated with it a matter of worldwide concern. Several research thus focus on hepatoprotection .Preventive and therapeutic activity plants as hepatoprotective agent is topic interest for researchers. Hepatotoxic agents like carbon tetrachloride, paracetamol, isoniazide etc. increase the serum biomarkers liver where ALT more specifi...
The present study seeks to evaluate the alcoholic extract of aerial part of H.Sanguinea for its anti-hepatotoxic effect against carbon tetrachloride (CCl4)
Paraphenylenediamine (PPD) is a chemical product used in hair dye preparations and temporary tattoos to fasten the dyeing process intensify its results. PPD can evoke local and/or systemic toxic effects either when utilized topically, inhaled or ingested. The aim of this study was evaluate on liver adult female albino rats. Thirty-two rats were divided into 3 groups. Group I (control group) 16 ...
Drug- and alcohol-induced liver injury are a leading cause of liver failure and transplantation. Emerging evidence suggests that extracellular vesicles (EVs) are a source of biomarkers because they contain unique proteins reflecting the identity and tissue-specific origin of the EV proteins. This study aimed to determine whether potentially hepatotoxic agents, such as acetaminophen (APAP) and b...
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