The intracellular sites of glycogen degradation in the mid to late uterine chick embryo were determined by cytochemical localization of glucose-6-phosphatase at the ultrastructural level. Enzyme activity was found between the two membranes of the nuclear envelope, in the annulate lamellae and in specialized glycogen-containing membrane scrolls. Annulate lamellae and glycogen scrolls were most f...

Levels of cardiac glycogen were determined by biochemical assays in turkey poults from an experimental flock with a known high incidence of round heart disease. Levels of cardiac glycogen were significantly higher (p < .05) than in commercial turkeys, but not significantly different in the turkeys that developed spontaneous round heart disease. The high level of cardiac glycogen in the poults o...

A case of hereditary fructose intolerance is reported in a girl aged 2 years at the time of her death. She had apparently progressed normally until the age of 14 months. At 19 months she was admitted to hospital with failure to thrive, hepatomegaly, and superficial infections. Investigations revealed hypoglycaemia, persistent acidosis, aminoaciduria, and a high liver glycogen level which sugges...

The regulatory role of protein kinase C (PKC) in glycogen metabolism in pectin fed rats was investigated. Administration of pectin (5 g/kg body wt/day) from cucumber (Cucumis sativius L.) led to inhibitory effects on PKC activity in the liver of rats. In the brain and pancreas, PKC activity was significantly higher in pectin-treated rats as compared to the control group. Level of blood glucose ...

Glycogen is a multi-branched polysaccharide of glucose that serves as a form of energy storage in animals. The present paper deals with changes in the level of glycogen in Clarias batrachus, which was subjected to prolonged fasting of 40 days. Tissues of brain were selected for the study. Glycogen content was estimated by the calorimetric method of Kemp et al. (1954) as modified by Krishnaswamy...

Background High-intensity exercise typically leads to a depletion of body carbohydrate stores, primarily muscle glycogen. Therefore, typical ‘sports recovery drinks’ include a high carbohydrate dose, which stimulate muscle glucose uptake and glycogen re-synthesis via increased plasma insulin level. Thus, interventions that elevate plasma insulin following exercise could facilitate repletion of ...

Herbal medicine development against the non-communicable disease like diabetes is one of the thrust area of research in the field of global medicine. Here we have studied the separate and composite methanolic extract of seed of Eugenia jambolana and root of Musa paradisiaca for the management of streptozotocin-induced diabetes mellitus. We have measured the fasting blood glucose level and glyco...

A small portion of cellular glycogen is transported to and degraded in lysosomes by acid α-glucosidase (GAA) in mammals, but it is unclear why and how glycogen is transported to the lysosomes. Stbd1 has recently been proposed to participate in glycogen trafficking to lysosomes. However, our previous study demonstrated that knockdown of Stbd1 in GAA knock-out mice did not alter lysosomal glycoge...

football participation requires considerable utilization of both aerobic and anaerobic energy systems to match the high energetic demands of the sport. the consequent stresses imposed on the physiological and metabolic systems carries players to the threshold of exhaustion during match-play, from which they are required to recover in preparation for the subsequent game. a high number of players...

The regulatory-targeting subunit (RGL), also called GM) of the muscle-specific glycogen-associated protein phosphatase PP1G targets the enzyme to glycogen where it modulates the activity of glycogen-metabolizing enzymes. PP1G/RGL has been postulated to play a central role in epinephrine and insulin control of glycogen metabolism via phosphorylation of RGL. To investigate the function of the pho...