نتایج جستجو برای: glipizide

تعداد نتایج: 326  

Journal: :Diabetes care 2002
William T Cefalu David J Schneider Harold E Carlson Phyllis Migdal Leonil Gan Lim Meriam P Izon Anoop Kapoor Audrey Bell-Farrow James G Terry Burton E Sobel

OBJECTIVE Epidemiological studies have implicated increased plasminogen-activated inhibitor 1 (PAI-1) as a marker or predictor of accelerated coronary atherosclerotic disease in type 2 diabetes. We sought to determine whether metabolic control, independent of its oral mode of implementation, affects PAI-1 in patients with marked hyperglycemia. RESEARCH DESIGN AND METHODS A total of 91 subject...

Journal: :Journal of the Endocrine Society 2019

2011
Kyeong Won Lee Yun Hyi Ku Min Kim Byung Yong Ahn Sung Soo Chung Kyong Soo Park

BACKGROUND Sulfonylurea primarily stimulates insulin secretion by binding to its receptor on the pancreatic β-cells. Recent studies have suggested that sulfonylureas induce insulin sensitivity through peroxisome proliferator-activated receptor γ (PPARγ), one of the nuclear receptors. In this study, we investigated the effects of sulfonylurea on PPARγ transcriptional activity and on the glucose ...

2015
Geoffrey A. Walford Natalia Colomo Jennifer N. Todd Liana K. Billings Marlene Fernandez Bindu Chamarthi A. Sofia Warner Jaclyn Davis Katherine R. Littleton Alicia M. Hernandez Rebecca R. Fanelli Amelia Lanier Corinne Barbato Rachel J. Ackerman Sabina Q. Khan Rosa Bui Laurel Garber Elliot S. Stolerman Allan F. Moore Chunmei Huang Varinderpal Kaur Maegan Harden Andrew Taylor Ling Chen Alisa K. Manning Paul Huang Deborah Wexler Rita M. McCarthy Janet Lo Melissa K. Thomas Richard W. Grant Allison Goldfine Margo S. Hudson Jose C. Florez

OBJECTIVE Genome-wide association studies have uncovered a large number of genetic variants associated with type 2 diabetes or related phenotypes. In many cases the causal gene or polymorphism has not been identified, and its impact on response to anti-hyperglycemic medications is unknown. The Study to Understand the Genetics of the Acute Response to Metformin and Glipizide in Humans (SUGAR-MGH...

2013
SELLAPPAN VELMURUGAN

The aim of study was to prepare and characterize mucoadhesive buccal tablets of glipizide using different Mucoadhesive polymers such as Carbopol 940, Sodium alginate and HPMC K15M in combination. Twenty one formulation were developed with different concentration of mucoadhesive polymers in each formulation.The formulated buccal tablets were tested for surface pH,in vitro drug release and moistu...

2009
KAJAL GHOSAL

The aim of the present investigation was to investigate the effect of chemical enhancers on the release of glipizide through transdermal matrix patch using different ratio of different chemical enhancers. L-menthol, oleic acid and n-octanol were tried over the glipizide matrix patch. The used concentrations of L-menthol and oleic acid were 1%, 1.5% and 2.0% and concentration of n-octanol was 1%...

Journal: :Canadian family physician Medecin de famille canadien 2009
Miguel Marcelo Glatstein Nada Djokanovic Facundo Garcia-Bournissen Yaron Finkelstein Gideon Koren

QUESTION My patient was taking glipizide (an oral sulfonylurea) for type 2 diabetes. Now she is pregnant and taking insulin instead. She is very anxious to return to her previous treatment immediately after delivery because of the pain and hurdles associated with the administration of insulin. Can sulfonylureas cross into human milk and, if so, is it safe for her to breastfeed her infant? ANS...

Journal: :Acta poloniae pharmaceutica 2012
Asish Biswas Suparna Chatterjee Rama Chowdhury Sangita Sen Dipak Sarkar Mitali Chatterjee Jayasree Das

The antidiabetic effect of seeds of Strychnos potatorum Linn. was evaluated in a model of diabetes mellitus using streptozotocin (40 mg/kg b.w., i.p.). Changes in fasting blood sugar were estimated periodically for 12 weeks along with weekly measurement of body weight, food and water intake for 4 weeks. The antidiabetic effects were compared with glipizide as the reference hypoglycemic drug. St...

2013
Anita Singh M. Vijaykumar

Now a day transdermal drug deliveries are increasing rapidly for the treatment of various diseases so the present study was conducted on different penetration enhancers for permeation of antidiabetic drug, glipizide (sulfonyl urea derivative) through skin. Different types of penetration enhancers such as terpenes and terpenoids, pyrrolidones, oxazolidinones, fatty acids etc are used for permeat...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید