The multiple species de novo gene prediction problem can be stated as follows: given an alignment of genomic sequences from two or more organisms, predict the location and structure of all protein-coding genes in one or more of the sequences. Here, we present a new system, N-SCAN (a.k.a. TWINSCAN 3.0), for addressing this problem. N-SCAN can model the phylogenetic relationships between the alig...

background uropathogenic escherichia coli (upec) is a causative agent of most of urinary tract infections (utis), which expresses a multitude of virulence factors. objectives the aim of this study was to investigate virulence associated characteristics characteristics in upec isolates derived from urine specimens, and to investigate the distribution of the pathogenicity islands virulence marker...

dermatophytes are a group of keratinophilic fungi capable of invading keratinized tissues (skin, hair and nails). they cause dermatophytosis (commonly known as tinea or ring worm) in human and animals. in this report, dna similarities and genomic linkage of 40 dermatophytes strains was obtained from different universities, were studied by random amplified polymorphic dna (rapd–pcr) using 11 ran...

Hybridization is increasingly being recognized as a common process in both animal and plant species. Negative epistatic interactions between genes from different parental genomes decrease the fitness of hybrids and can limit gene flow between species. However, little is known about the number and genome-wide distribution of genetic incompatibilities separating species. To detect interacting gen...

Phenotypically discordant monozygotic twins offer the possibility of gene discovery through delineation of molecular abnormalities in one member of the twin pair. One proposed mechanism of discordance is postzygotically occurring genomic alterations resulting from mitotic recombination and other somatic changes. Detection of altered genomic fragments can reveal candidate gene loci that can be v...

background: nematodes are among the most common and important parasites of man and animal. dna of a single worm can be used for several purposes, such as identification to the species, subspecies, strain and antihelmenthic resistance. dna extraction from a single small worm using traditional methods such as phenol extraction technique faces serious prob lems. methods: dna from 20 single haemonc...

ct image quality has been affected by many factors such as kvp, ma, exposure time, alogorithm and section thickness. gantry tilt has the main role in visualization of the temporal bone anatomic structures. in this study, we tried to optimize these factors to determine the best gantry tilt. this study was performed on the human skull phantom and then extended to 15 patients. the phantom was made...

Domestications and selection have led to phenotypic variation in chicken and has left traceable signatures within their genome. Indigenous chicken has been shaped more by natural selection [1] imposed by the environmental conditions, parasites, diets and diseases. Several candidate genes that contribute to adaptation to harsh scavenging tropical conditions, for instance, those linked to respons...