genomic selection is a method to predict the breeding values of individuals using a large number of single nucleotide polymorphism markers. the cost of the high-density marker panel genotyping is very high, which prevents the widely application of genomic selection. the present simulation study was carried out to evaluate the use of low to medium marker density panels to predict direct genomic ...

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UNLABELLED IGIPT is a web-based integrated platform for the identification of genomic islands (GIs). It incorporates thirteen parametric measures based on anomalous nucleotide composition on a single platform, thus improving the predictive power of a horizontally acquired region, since it is known that no single measure can absolutely predict a horizontally transferred region. The tool filters ...

A gene mediating interactions between mouse mothers and their pups has recently been claimed to support coadaptation rather than the kinship theory of genomic imprinting. This Formal Comment argues that this claim is unfounded.

Genome-wide evaluation uses the associations of a large number of single nucleotide polymorphism (SNP) markers across the whole genome and then combines the statistical methods with genomic data to predict the genetic values. Genomic predictions relieson linkage disequilibrium (LD) between genetic markers and quantitative trait loci (QTL) in a population. Methods that use all markers simultaneo...

Hymenolepis nana is a common parasite of rodents as well as human intestine. This parasite has beenreported from all over the world, including Iran. The infection rate has been reported up to 40% in someareas. The infection has various clinical manifestations. The parasite could establish severe hyperinfection inpatients with immune deficiency. Regarding the rodents as hosts of the parasite, th...

abstract: colorectal cancer (crc) is the third most common cancer in men and the second most common cancer in women worldwide. both genetic and epigenetic alterations are common in crc and are the driving force of tumorigenesis. chromosomal instability, microsatellite instability and cpg island methylator phenotype pathways are responsible for genetic instability in colorectal cancer. chromosom...

Common fragile sites are specific regions in the human genome that are particularly prone to genomic instability under conditions of replicative stress. Recent data suggest that these sites depend on the checkpoint kinase ATR to maintain their stability.