1,8-dioxo-decahydroacridines have been synthesized by the three-component reaction of aromatic aldehydes, aromatic amines (or ammonium acetate), and dimedone in the presence of sulfonic acid functionalized nanoporous silica (sba-pr-so3h) under solvent-free conditions. excellent yields, short reaction times, mild reaction conditions, and easy work-up procedures are advantages of this green method.

decatungstodivanadogermanic acid (h6gew10v2o40.22h2o) was used as a green heterogeneous catalyst for the synthesis of 3,4-dihydropyrimidin-2-(1h)-ones from one-pot three-component cyclocondensation reaction of a β-ketoester, an aldehyde and urea/thiourea under solvent-free conditions is reported. this method provides an efficient and much improved modification of the original biginelli reaction...

A convenient and highly efficient procedure for the synthesis of 3,4-dihydropyrimidin-2-(1H)-one/thione derivatives via one-pot three-component Biginelli condensation of arylaldehydes,urea/thiourea and ethyl/methyl acetoacetate in the presence of Zn(SO4)2.7H2Oas anefficient, readily and inexpensive catalyst under solvent-free conditions have been studied. Thisprotocol ha...

a highly efficient, simple and green solvent-free protocol for the preparation of poly-substituted quinolines via friedländer hetero-annulation reaction between 2-aminoaryl ketones and carbonyl compounds in the presence of silica-supported p2o5 (p2o5 / sio2) is described. in this method, the title compounds are obtained in high to excellent yields and in short reaction times.

silica-bonded n-propyltriethylene-tetramine (sbnptt) was found as an efficient solid base for the synthesis of 2-amino-5-oxo-5,6,7,8-tetrahydro-4h-chromenes. chromene derivatives were obtained via the three-component condensation reaction of aromatic aldehydes, malononitrile, and dimedone at 80 oc under solvent-free conditions. the heterogeneous solid base showed much the same efficiency when u...

silica-bonded n-propyldiethylenetriamine sulfamic acid (spdtsa) is employed as a recyclable heterogeneous solid acid catalyst for the synthesis of benzopyrano[2,3-d]pyrimidines  through one-pot condensation reaction of salicylaldehydes, malononitrile and secondary amines  at room temperature under solvent-free conditions. spdtsa showed much the same efficiency when used in consecutive reaction ...

this work described an efficient pseudo four-component synthesis of (10e)-n-benzylidene-2-phenylh-imidazo[1,2-a]pyridin-3-amine derivatives from 2-aminopyridin, malononitrile and arylaldehydes in the presence of naoh under solvent-free and conventional heating condition in good to excellent yields. a wide range of aromatic aldehydes would easily undergo condensations with 2-aminopyridin and mal...

A convenient synthetic method for the synthesis of 2,4,5-trisubstituted and 1,2,4,5-tetra substituted imidazole derivatives, has been developed via one-pot condensation reaction in solvent-free condition when aldehyde, ammonium acetate/amine, and 1,2-diketone are reacted using 0.8 mol% of NP-LaMnO3 at 80 °C under solvent free conditions. Catalyst could be recovered and reused in five reaction c...

the synthesis of functionalized 2-oxo-2h-coumarin derivatives has been studied by a one-pot reaction of o-hydroxybenzaldehyde, ethyl 2-bromoacetate and triphenylphosphine in the presence of catalytic amount of triethyl amine in etoac, water or under solvent free conditions. we have found the best results obtained under solvent free condition.

A convenient synthetic method for the synthesis of 2,4,5-trisubstituted and 1,2,4,5-tetra substituted imidazole derivatives, has been developed via one-pot condensation reaction in solvent-free condition when aldehyde, ammonium acetate/amine, and 1,2-diketone are reacted using 0.8 mol% of NP-LaMnO3 at 80 °C under solvent free conditions. Catalyst could be recovered and reused in five reaction c...