OBJECTIVE To examine whether dietary intake of specific flavonoid subclasses (including flavonols, flavones, flavanones, flavan-3-ols, anthocyanins, and flavonoid polymers) is associated with weight change over time. DESIGN Three prospective cohort studies. SETTING Health professionals in the United States. PARTICIPANTS 124,086 men and women participating in the Health Professionals Follo...

Diets rich in flavonoids have been reported to have beneficial effects in the primary prevention of cardiovascular events. There are limited data, however, on the cardiovascular benefits of purified flavonoids. The aim of this systematic review and meta-analysis was to examine the reported effects of isolated flavonoids on aortic atherosclerosis in a mouse model. Medline, Pubmed, Science direct...

In the present study the amount of three important flavonols (kaempferol, quercetin, myricetin) and five phenolic acids (gallic acid, ferulic acid, cinnamic acid, vanillic acid and caffeic acid) were determined from four medicinally important indigenous plants like Euphorbia tirucalli, Trigonella foenum-graecum, Cyperus rotundus and Rheum emodi. Methanolic extracts of native parts and gemmo-mod...

Flavanols and flavonols of mitotic and post-mitotic nuclei in needles of Taxus baccata L., Tsuga canadensis L., and slow growing dwarf genotypes of both genera are investigated histochemically. The flavanols of nuclear chromatins and in the vacuoles stain blue with the p-dimethylamino-cinnamaldehyde (DMACA) reagent. Flavonols do not react with the reagent but owing to their UV absorbance they c...

Several species of Nicotiana and Solanum and further members of the Solanaceae have been examined for their exudate flavonoids. Most of the aglycones are widespread flavonols, but rare and unusual flavonols were also found, e.g. in exudates of Physalis and Solanum species. Flavones occur throughout the family, but flavanones are rare. Our data are presented in comparison to previous results. Th...

SCOPE Insulin-regulated glucose metabolism in cells is critical for proper metabolic functioning, and insulin resistance leads to type 2 diabetes. We performed a human study to assess the availability of structurally related dietary flavonols and tested their ability to affect cellular glucose uptake, metabolism, and glucose transporter gene expression in a liver HepG2 cell model. METHODS AND...

This study comprises the optimization and validation of a new TLC method for determination of flavonols in the bulbs of seven cultivars of onions and shallots. Separation was performed on RP-18 plates with the solvent mixture tetrahydrofuran/water/formic acid (40+60+6, V/V/V) as a mobile phase. The method was evaluated for precision, linearity, LOD, LOQ, accuracy and robustness. Chromatographic...

Flavonol glycosides in tea leaves have been quantified as aglycones, quercetin, myricetin, and kaempferol. Occurrence of the said compounds was reported in fruits and vegetable for a long time in association with the antioxidant potential. However, data on flavonols in tea were scanty and, hence, this study aims to envisage the flavonol content in a representative pool of accessions present in ...

Plant domestication can have negative consequences for defensive traits against herbivores, potentially reducing the levels of chemical defenses in plants and consequently their resistance against herbivores. We characterized and quantified the defensive flavonols from multiple cultivated ecotypes with wild ancestors of murtilla, Ugni molinae Turcz, an endemic plant from Chile, at different tim...

Illicium verum (badiane or star anise), Crataegus oxyacantha ssp monogyna (hawthorn) and Allium cepa (onion), have traditionnally been used as medicinal plants in Algeria. This study showed that the outer layer of onion is rich in flavonols with contents of 103 ± 7.90 µg/g DW (red variety) and 17.3 ± 0.69 µg/gDW (white variety). We also determined flavonols contents of 14.3 ± 0.21 µg/g 1.65 ± 0...