labor is a physiological event involving a sequential, integrated set of changes within the myometrium, deciduas, and uterine cervix that occur gradually over a period of days to weeks. biochemical connective tissue changes in the uterine cervix appear to precede uterine contractions and cervical dilation, and all of these events usually occur before rupture of the fetal membranes. in other wor...

background: several studies have assessed the correlation of fetal choroid plexus cyst (cpc) and the risk of congenital anomalies, but few ones have discussed isolated cpc (with no other abnormal sonographic finding). objective: the aim of this study was to determine the outcome of isolated fetal choroid plexus cyst and to specify its clinical significance. materials and methods: this cross sec...

Iron-containing proteins catalyze lipid peroxidation when combined with either H2O2 or ascorbic acid (ASC). Microsomal membranes were prepared from Day 13 endometrial and conceptus tissues (5 pigs) and from Day 30 endometrial, placental, fetal liver, and fetus minus fetal liver tissues (5 pigs). Microsomal membranes were subjected to the following in vitro treatments: 1) no treatment, 2) 50 mic...

The mechanisms that regulate the induction of term or preterm delivery (PTD) are not fully understood. Infection is known to play a role in the induction of pro-inflammatory cascades in uteroplacental tissues associated with preterm pathological parturition. Similar but not identical cascades are evident in term labour. In the current study, we used a mouse model to evaluate the role of prokine...

In previous papers [l, 6] it was reported that the rupture of membranes facilitates the production of type I dips in the fetal heart rate (FHR) tracing. This Statement is based on the effect of amniotomy on FHR records [6] and also on the quantitative study of a group of 26 monitored labors induced with oxytocin [1], in which membranes were artificially ruptured when cervical dilatation was bet...

BACKGROUND Human labor is a complex series of cellular and molecular events that occur at the materno-fetal and uterine levels. Many hypotheses have been proposed for the initiation of human labor, one hypothesis suggests that maturation of the fetus releases a signal in the amniotic fluid that will be transmitted to myometrium via the fetal membranes and initiate uterine contractions. There is...

The frequency of spontaneous premature rupture of membranes (PROM) was determined in the pregnancies of 1,848 white mothers and their singleton infants, born at the University of Kansas Medical Center between April 1975 and April 1978. The frequency of PROM increased significantly from a low of 34/707 (4.8 percent) among low-risk mothers, to 40/444 (9.0 percent) among mothers smoking one to 60 ...

STUDY QUESTION Are the fetal membranes of women affected with endometriosis similar to those from disease-free women? SUMMARY ANSWER Decidua of women with endometriosis is able to generate endometriotic-like lesions in contact with the fetal membranes. WHAT IS KNOWN ALREADY Eutopic endometrium of women affected with endometriosis presents compromised properties. Endometrium undergoes decidu...