ADAM-15, with known zymogen, secretase, and disintegrin activities, is a catalytically active member of the ADAM family normally expressed in early embryonic development and aberrantly expressed in various cancers, including breast, prostate and lung. ADAM-15 promotes extracellular shedding of E-cadherin, a soluble ligand for the HER2/neu receptor, leading to activation, increased motility, and...

This article paper aims to verify a posible methodological detour made by Hegel on his work Philosophy of Religion, precisely Reading Genesis 3. During the text, german autor take path in sense identify men’s nature origin and fundamentals coexistence between good ande vil own. It happens that affirms snake didn’t tricked First Couple, but just inducted them, way if Adam Eve eated from Good Evi...

ADAM metalloprotease-disintegrins share a common modular structure of functional domains for proteolytic, cell adhesion, and signaling interactions. The metalloprotease domain of oughly half of the known ADAMs contain an intact consensus metzincin catalytic site, and they are thus thought to function as active metalloproteases. The types of interactions mediated by ADAMs are expressly conspicu...

as one of the most unfathomable mysteries human beings encounter with, death has always been one of the main concerns of great scholars and one of the major teachings of monotheistic religions. augustine is one of the great scholars who reflect upon and talk about death. interestingly, we do not face with a particular definition of death in augustine’s works. as a platonic philosopher, he consi...