A 5 year-old boy with a cerebellar gangliocytoma with a peripheral right facial paresis and ataxia is presented. His MRI showed a heterogenous, diffuse lesion, isointense on T1 and hyperintense on T2-weigthed sequences, involving the right cerebellar hemisphere with direct extension into the right facial nerve. The present case is the first description of a gangliocytoma with direct facial nerv...

Cowden syndrome (CS), also known as multiple hamartoma-neoplasia syndrome, is an autosomal dominant disease with numerous possible clinical manifestations. Commonly present are skin changes including acral keratoses and facial trichilemmomas, as well as oral papillomas and scrotal tongue. There is an increased risk of malignancies including breast, thyroid, and endometrial cancers. Hamartomas m...

Ganglion cell tumors (GCT) are divided into two subtypes : gangliocytoma and ganglioglioma. Intramedullary gangliocytomas are extremely rare. A 20-year-old male patient with pain of neck, who also had a previously known neuroendocrine tumor of lung, was operated for mass found in the cervicomedullary junction with a presumptive diagnosis of metastases. Only partial resection could be performed....

syndrome. The cerebellum within those cephaloceles is usually dysplastic and gliotic. Plexiform NF, hallmark of NF-I are found in 30-40% of all patients with NF-I. They usually arise along the axis of a major nerve, are unencapsulated and infiltrate producing fusiform appearance. They commonly occur along orbital division of V nerve, but other areas are not exempt often associated with sphenoid...

The monoclonal antibody A60 specifically recognizes the DNA-binding, neuron-specific protein NeuN, which is present in most neuronal cell types of vertebrates. In this study we demonstrate the potential use of NeuN as a diagnostic neuronal marker using a wide range of formalin-fixed, paraffin-embedded human surgical and autopsy specimens from the central and peripheral nervous system. After mic...