The possibility to release drugs from conducting polymers, like polypyrrole or poly(3,4-ethylenedioxythiophene) (PEDOT), has been described and investigated for a variety of different substances during the last years, showing a wide interest in these release systems. A point that has not been looked at so far however is the possibility of other substances, next to the intended ones, leaving the...

the design and application of a fuzzy logic based controller to a leakage current relay waspresented in this paper. a novel approach based on fuzzy logic to form the tripping action of leakagecurrent relay was investigated. in addition to the theoretical aspect of fuzzy logic, detection of a leakagecurrent, measurement of the leakage current, determination of its duration, trip opening of fault...

Recent advances in medications for neurodegenerative disorders are expanding opportunities for improving the debilitating symptoms suffered by patients. Existing pharmacologic treatments, however, often rely on systemic drug administration, which result in broad drug distribution and consequent increased risk for toxicity. Given that many key neural circuitries have sub-cubic millimeter volumes...

Introduction: Peripheral Intravenous catheterization is the most commonly used invasive treatment method in patients admitted to the hospitals, but it has some complications. The indwell time of catheter is one of the factors associated with the occurrence of complications, especially phlebitis. In spite of the instructions for replacing the catheters after 72 hours, sometimes the complications...

A self-folding miniature device has been developed to provide enhanced mucoadhesion, drug protection, and targeted unidirectional delivery. The main part of the device is a finger like bilayered structure composed of two bonded layers. One is a pH-sensitive hydrogel based on crosslinked poly(methyacrylic acid) (PMAA) that swells significantly when in contact with body fluids, while the other is...

The economic and environmental losses due to serious leakage in the urban water supply network have increased the effort to control the water leakage. However, current methods for leakage estimation are inaccurate leading to the development of ineffective leakage controls. Therefore, this study proposes a method based on the blind source separation theory (BSS) to calculate the leakage of water...

one of the important factors influencing outdoor insulators performance is pollution phenomenon. the pollution, especially during humidity condition, reduces superficial resistance of insulator and lead to a flow of leakage currents (lc) on the insulator surface, which may result in total flashover. the lc characteristics are affected by parameters such as nature and severity of pollution. loca...

PURPOSE Small injection ports for mice are increasingly used for drug testing or when administering contrast agents. Commercially available mini-ports are expensive single-use items that cause imaging-artifacts. We developed and tested an artifact-free, low-cost, vascular access mini-port (VAMP) for mice. PROCEDURES Leakage testing of the VAMP was conducted with high speed bolus injections of...

The Ocusert-pilocarpine devides with seven days' therapeutic duration were compared with pilocarpine eye drops for efficacy and ocular tolerance in the management of glaucoma in 16 patients. Magnitude of pressure reduction with release rates of 20 mcg. and 40 mcg. of pilocarpine per hour were as effective in the treatment of glaucoma as 2 per cent and 4 per cent pilocarpine eye drops, respectiv...