introduction in neonates and small infants, early diagnosis of central diabetes insipidus (cdi) and treatment with desmopressin in low doses (avoiding severe hypo- or hypernatremia) are important to prevent associated high morbidity and mortality in this particular age group. case presentetion we described pharmacokinetic and pharmacodynamic results of the use of recently launched oral desmopre...

Optically stimulated luminescence nanoDot dosimeters (OSLD) have been used to measure single point dose distribution along the superior-inferior position at the surface (skin) and in depths, analogous to organ depths. A customized acrylic phantom of 46 cm length, 20 cm diameter was fabricated, and used for the experimental measurements using CT (Computed Tomography) beam. The CT dose profile al...

background: dose calculation algorithms play a very important role in predicting the explicit dose distribution. we evaluated the percent depth dose (pdd), lateral depth dose profile, and surface dose volume histogram in inhomogeneous media using calculation algorithms and inhomogeneity correction methods. materials and methods: the homogeneous and inhomogeneous virtual slab phantoms used in th...

CONTEXT The present review aimed at reviewing the effects of different statins on lipid profile, particularly in Asians. EVIDENCE ACQUISITION PubMed searches were conducted using the keywords 'statin, effect, and lipid profile' from database inception through March 2016. In this review, 718 articles were retrieved from the primary search. After reviewing the titles, abstracts, and full texts,...

Introduction: Nonsteroidal anti-inflammatory drugs are the most commonly used drugs to reduce pain and inflammation. Aceclofenac is a newer derivative of diclofenac with less gastrointestinal complications. The objective of the present study was to evaluate the toxicity profile of sustain release aceclofenac injection in rats at three dose levels, ranging from 2 to 10 mg/kg body weight. Mater...

Introduction Magnetic fields are capable of altering the trajectory of electron beams andcan be used in radiation therapy.Theaim of this study was to produce regions with dose enhancement and reduction in the medium. Materials and Methods The NdFeB permanent magnets were arranged on the electron applicator in several configurations. Then, after the passage of the electron beams (9 and 15 MeV Va...

Background: Calcineurin inhibitors (CNI) have significantly reduced the incidence of acute rejection. Nephrotoxicity however may contribute to long-term allograft dysfunction. Mycophenolate mofetil (MMF) may allow cyclosporine (CsA) dose reduction without increasing the risk of rejection. Methods: In seventy-eight living unrelated kidney transplant patients with renal dysfunction, we studi...

Aromatase inhibitors (AI) profoundly suppress estrogen levels in postmenopausal women and are effective in breast cancer prevention among high-risk postmenopausal women. Unfortunately, AI treatment is associated with undesirable side effects that limit patient acceptance for primary prevention of breast cancer. A double-blind, randomized trial was conducted to determine whether low and intermit...