Rosai-Dorfman disease is a rare histiocytic disorder, clinically characterized by massive, bilateral painless cervical lymphadenopathy with potential for extranodal manifestations. We report a 45-year-old male patient who presented with a slowly growing erythematous nodule of the left chin. The mass appeared non-vascular on computed tomography study, but ultrasonogram was suggestive of a vascul...

A 61-year old female presented with a headache. CT and MR imaging showed a left frontal dural-based mass mimicking meningioma. H-MR spectroscopy showed elevated lipid peaks and decreased N-aspartate, choline and creatine peaks. No abnormal alanine peak was detected. The histological diagnosis was intracranial Rosai-Dorfman disease. Our case suggests that H-MR spectroscopy provides useful inform...

Rosai-Dorfman disease (also known as sinus histiocytosis with massive lymphadenopathy) is a rare benign proliferative disorder of histiocytes that typically involves the lymph nodes and can also involve extranodal sites. Rosai-Dorfman disease confined to the breast is extremely rare, but important to recognize as it can mimic malignancy. We present the case of a 63-year-old woman who presented ...

A young male presented with recurrent neck swellings with initial leucocyte count of 16800/mm3, with non-caseating glands on ultrasonography neck. FNAC showed mixed cellularity with histiocytic and marked lymphophagocytosis as seen in Rosai Dorfman Disease. Immunohistochemistry demonstrated CD 25, Ki 67 and CD 68 in histiocytes. Her responded to supportive treatment alone.

CRDD: cutaneous Rosai-Dorfman disease LCH: Langerhans cell histiocytosis RDD: Rosai-Dorfman disease R osai-Dorfman disease (RDD) is a benign histiocytic proliferation that most commonly presents with painless bilateral lymphadenopathy and constitutional symptoms such as fever, fatigue, and night sweats. RDD is considered by many to be a reaction pattern with several different manifestations, es...

Rosai-Dorfman disease (also known as sinus histiocytosis with massive lymphadenopathy) is a rare benign proliferative disorder of histiocytes that typically involves the lymph nodes and can also involve extranodal sites. Rosai-Dorfman disease confined to the breast is extremely rare, but important to recognize as it can mimic malignancy. We present the case of a 63-year-old woman who presented ...

Rosai-Dorfman disease (RDD) is a rare benign proliferative disorder of histiocytes in the lymph nodes with or without extranodal involvement. RDD limited to the skin without nodal involvement, known as cutaneous Rosai-Dorfman disease, is very rare. We describe a 34-year-old female with RDD of the skin over the chest. A large nodule with satellite lesions was excised for histopathological examin...

231 Received March 23, 2012; revision accepted for publication June 21, 2012. doi: 10.1620/tjem.227.231 Correspondence: Shingo Noguchi, M.D., Department of Respiratory Medicine, University of Occupational and Environmental Health, Iseigaoka, Yahatanishiku, Kitakyushu city, Fukuoka 807-8555, Japan. e-mail: [email protected] Intrathoracic Rosai-Dorfman Disease with Spontaneous Remission: A ...