Two strains of Aedes aegypti, one resistant to DDT but susceptible to permethrin(RdSp), and the other resistant to both DDT and permethrin (RdRp), were established in mosquitoes collected from Chiang Mai province, northern Thailand. Comparisons with a susceptible reference strain indicated that DDT resistance in both RdSp and RdRp strains was mainly due to an increase in DDTase activity. Simila...

Resistance is threatening the effectiveness of insecticide-based interventions in use for malaria control. Pinpointing genes associated with resistance crucial evidence-based management targeting major vectors. Here, a combination RNA-seq based genome-wide transcriptional analysis and RNA-silencing vivo functional validation were used to identify key insecticide DDT DDT/permethrin cross-resista...

The Rst(2)DDT locus (loci) in Drosophila is associated with the over-expression of two cytochrome P450 genes, Cyp6g1 and Cyp12d1. Using northern and western blot analysis we observed the expression pattern of these two genes in two DDT susceptible (Canton-S and 91-C) and three DDT resistant strains (Wisconsin, 91-R and Hikone-R). In Canton-S and 91-R, the CYP6G1 protein was constitutively expre...

Contact with the pesticide dichlorodiphenyltrichloroethane (p,p′-DDT) can be the cause of various harmful effects in humans, wildlife, and the environment. This pesticide is known to be persistent, lipophilic, resistant to degradation, and bioaccumulive in the environment and to be slowly released into bloodstream. Growing evidence shows that exposure to DDT is linked to type 2 diabetes mellitu...

OBJECTIVES To investigate the DDT and deltamethrin susceptibility of Phlebotomus argentipes, the vector of Leishmania donovani, responsible for visceral leishmaniasis (VL), in two countries (India and Nepal) with different histories of insecticide exposure. METHODS Standard WHO testing procedures were applied using 4% DDT and 0.05% deltamethrin impregnated papers. The effect of the physiologi...

A. W. A. BROWN It is now 21 years since DDT -resistant house flies were first discovered in northern Sweden, and since the report of Wilson and Gahan that a DDT -resistant strain could be produced by laboratory selection at Orlando. Although the resistance of the San Jose scale to lime-sulfur was detected by Melander in Washington state nearly 60 years ago, the resistance problem as we know it ...

BACKGROUND Despite the recent progress in establishing the patterns of insecticide resistance in the major malaria vector Anopheles funestus, Central African populations of this species remain largely uncharacterised. To bridge this important gap and facilitate the implementation of suitable control strategies against this vector, we characterised the resistance patterns of An. funestus populat...

BACKGROUND & OBJECTIVE Japanese encephalitis (JE) outbreaks are common in Assam, northeastern State of India. Information on resistance in known JE vectors in the affected area is important for effective control measures. This study was undertaken to determine the species abundance of JE vectors endemic to Sibsagar district of Assam, and their susceptibility against DDT and deltamethrin. METH...

BACKGROUND According to the national strategy plan on monitoring of insecticides resistance, this study was carried out to determine the base line susceptibility of the Culicidae mosquitoes to the WHO-recommended insecticides in an endemic focus of malaria in southeastern Iran. METHODS Larval collection was carried out by dipping method and adult collection occurred by suction tube from Janua...

A strain (S) of Boophilus microplus collected from the east coast of New Caledonia was compared with a strain (R) from the west coast for resistance to deltamethrin. The R strain was significantly more resistant than strain S with a 5.7 fold resistance factor determined at the LDro using the larval packet technique. This is the first report of synthetic pyrethroid resistance in B. microplus in ...