If you have chronic back or neck pain, you may have degenerative disc disease. This degenerative spinal condition is not really a disease—it’s the normal wear and tear process of aging on your spine. Unfortunately, as we age, our intervertebral discs (pillow-like pads between the bones in your spine) lose their flexibility, elasticity, and shock absorbing characteristics. When this happens, the...

Study Design Retrospective study. Objectives To assess the fatty atrophy of the lumbar paraspinal muscles (LPMs) as determined using magnetic resonance imaging in patients with lumbar degenerative disk disease (DDD) and focal disk herniation and to determine if fatty atrophy is associated with patient-reported outcome measures (PROMS). Methods One hundred sixty-five patients with lumbar DDD wer...

OBJECTIVES The purpose of this research was to investigate the effect of using rate-adaptive pacing and atrioventricular interval (AVI) adaptation on exercise performance during cardiac resynchronization therapy (CRT). BACKGROUND The potential incremental benefits of using rate-adaptive pacing and AVI adaptation with CRT during exercise have not been studied. METHODS We studied 20 patients ...

The effects of DDD (fully automatic) and VVI (ventricular demand) pacing modes on exercise tolerance, symptom diary cards, and Holter monitoring were investigated in a randomised double blind crossover study of 16 patients who had had DDD pacemakers implanted because of frequent syncope. Eight patients presented with sick sinus syndrome and, with one exception, retrograde atrioventricular condu...

Apportioning pain and disability after a car accident or work related injury can be difficult. Many doctors who undertake this task often state that because an x ray examination or magnetic resonance imaging (MRI) scan soon after the injury shows degenerative disc disease (DDD), some or all of the patient’s spinal pain and disability must be pre-existing. This interpretation of imaging is not c...

Luka bakar merupakan salah satu bentuk trauma dengan tingkat risiko infeksi yang tinggi. Modalitas utama pada akibat luka ialah pemberian antibiotik. Tujuan penelitian ini untuk mengevaluasi penggunaan antibiotik pasien anak secara kualitatif menggunakan metode Gyssens dan kuantitatif ATC/defined daily dose (DDD). Pengambilan data dilakukan retrospektif melalui rekam medik memenuhi kriteria ink...

BACKGROUND Although serious mental illneses are treated with both typical and atypical antipsychotic grugs, trends in their use in psychiatric inpatient population in Israel are unrecognized. The aim of this study was to detect trends in the use of typical and atypical antipsychotic drugs in the Israeli inpatient psychiatric population throughout the last decade. METHODS Data regarding alloca...

Mitotane, 1,1-dichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane (o,p'-DDD) is an agent with adrenotoxic effect, which is able to block cortisol synthesis. This drug and radiotherapy are used also in adrenal cancer treatment even if their biological action in this neoplasia remains unknown. We investigated the effects of o,p'-DDD and ionizing radiations (IR) on cell growth inhibition and cell...

For patients suspected of having cerebral metastases, double-dose delayed CT (DDD-CT) has proved significantly more sensitive than CT scans obtained immediately after administration of a lesser dose of iodinated contrast material. Previous reports confirm the advantages of postcontrast MR imaging over contrast-enhanced CT, but data comparing DDD-CT and contrast-enhanced MR have not been reporte...

Sir, Dowling-Degos disease (DDD) is a rare disorder characterized by acquired pigmented macules and papules in a reticulate pattern, particularly affecting the flexural areas and other major skin folds (1, 2). A female patient presented with dotted and reticulate pigmentation of the axilla, and was diagnosed as DDD both clinically and histopathologically. However, the asymmetrical distribution ...