To study the chemical constituents and the effect of petroleum ether extracts on P-gp in Vitro. Compounds were isolated by methods of phase silica gel column chromatography, gel column chromatography, preparation of thin layer chromatography and various chromatographic techniques, and identified by the physicochemical data of spectral analysis. We measured P-glycoprotein(P-gp) mediated ATP hydr...

Objective: To study on anticancer effect in vitro and chemical compositions of root bark extracts of Acanthopanax henryi. Methods: The hot methanol extract of the root bark of A. henryi was through XAD-4 column chromatography eluting with a gradiennt of methanol in water. The anticancer effects of MeOH fractions were evaluated by MTT method. Then compounds were isolated by a combination of chro...

The use of α-glucosidase inhibitors is considered to be an effective strategy in the treatment of diabetes. Using a bioassay-guided fractionation technique, five Bacillus stearothermophilus α-glucosidase inhibitors were isolated from the flowers of Musa spp. (Baxijiao). Using NMR spectroscopy analysis they were identified as vanillic acid (1), ferulic acid (2), β-sitosterol (3), daucosterol (4)...

Dorema glabrum Fisch. & C.A. Mey. (Apiaceae) is a monocarpic perennial plant distributed in southern Caucasus. In Azerbaijan Republic folk medicine, the gum-resin of this species is used as a diuretic and anti-diarrheal agent. It is also traditionally used for the treatment of bronchitis and catarrh. In the present study, chemical constituents of the essential oil and extract of D. glabrum aeri...

Dorema glabrum Fisch. & C.A. Mey. (Apiaceae) is a monocarpic perennial plant distributed in southern Caucasus. In Azerbaijan Republic folk medicine, the gum-resin of this species is used as a diuretic and anti-diarrheal agent. It is also traditionally used for the treatment of bronchitis and catarrh. In the present study, chemical constituents of the essential oil and extract of D. glabrum aeri...

Lythrum salicaria L. (Lythraceae), a herbaceous plant growing widely in Iran, has been well known for many centuries for its astringent and styptic properties. A phytochemical investigation of this plant, based on spectroscopic analysis, identified fourteen compounds: 5-hydroxypyrrolidin-2-one (1), umbelliferone-6-carboxylic acid (2), 3,3',4'-tri-O-methylellagic acid-4-O-beta-D-(2"-acetyl)-gluc...

BACKGROUND Salvia, known as Maryam Goli in the Persian language, is an important genus that includes approximately 900 species in the Lamiaceae family. There are 58 Salvia species growing naturally in Iran, including Salvia chloroleuca Rech. f. and Allen., which grows wild in the northeastern and central parts of the country. OBJECTIVES This study was designed to determine the chemical compos...

More than 80% of the worldís population depend upon traditional medicines for various skin diseases (1). Recently, the traditional use of plants for wound healing has received attention by the scientific community (1, 2). Approximately one-third of all traditional medicines in use are for the treatment of wounds and skin disorders, compared to only 1-3 % of modern drugs (3). Wound healing is a ...