In this paper, we derive the Cramér-Rao bound (CRB) for range estimation, which does not only exploit the range information in the time delay, but also in the amplitude of the received signal. This new bound is lower than the conventional CRB that only makes use of the range information in the time delay. We investigate the new bound in an additive white Gaussian noise (AWGN) channel with atten...

Layered composite materials have become an increasingly interesting topic in industrial development. Cold roll bonding (CRB), as a solid phase method of bonding same or different metals by rolling at room temperature, has been widely used in manufacturing large layered composite sheets and foils. In this paper, we provide a brief overview of a technology using layered composite materials produc...

The evolutionarily conserved Crumbs (Crb) complex is crucial for photoreceptor morphogenesis and homeostasis. Loss of Crb results in light-dependent retinal degeneration, which is prevented by feeding mutant flies carotenoid-deficient medium. This suggests a defect in rhodopsin 1 (Rh1) processing, transport, and/or signaling, causing degeneration; however, the molecular mechanism of this remain...

This contribution considers carrier phase recovery in turbo receivers. We point out that the resulting Cramer-Rao bound (CRB) is close to its high signal-to-noise ratio (SNR) asymptote, even at the typical low operating SNR of turbo systems. We show that ‘code-unaware’ phase estimators are unable to perform closely to the CRB at the normal operating SNR of powerful codes. The advantage of ‘code...

Despite an increased interest in complex independent component analysis (ICA) during the last two decades, a closed form expression for the Cramér-Rao bound (CRB) for the demixing matrix is not known yet. In this paper, we fill this gap by deriving a closed-form expression for the CRB of the demixing matrix for instantaneous noncircular complex ICA. It contains the CRB for circular complex ICA ...

Mitosis is a fundamental process for chromosome segregation in all multicellular organisms. Misregulation of mitosis can cause genetic instability and cancer. Thus, identification of the genes involved in the regulation of mitosis is important for understanding the mechanism of chromosome segregation and genome instability. Unbiased genetic screens are powerful tools for identifying new gene fu...

Extreme helium stars (EHes) with effective temperatures from 8000 to 13 000 K are among the coolest EHes and overlap the hotter R CrB stars in effective temperature. The cool EHes may represent an evolutionary link between the hot EHes and the R CrB stars. Abundance analyses of four cool EHes, BD118 4381 (FQ Aqr), LS IV 2148 109, BD 218 3438 (NO Ser) and LS IV 218 002 (V2244 Oph), are presented...

BACKGROUND The CRB-65 score is a clinical prediction rule that grades the severity of community-acquired pneumonia in terms of 30-day mortality. AIM The study sought to validate CRB-65 and assess its clinical value in community and hospital settings. DESIGN OF STUDY Systematic review and meta-analysis of validation studies of CRB-65. METHOD Medline (1966 to June 2009), Embase (1988 to Nov...

OBJECTIVES We aimed to investigate suitable conditions of 8-hydroxy-2'-deoxyguanosine (8-OHdG) and micronucleus (MN) as genotoxic biomarkers at different levels of occupational chromate exposure. DESIGN A cross-sectional study was used. PARTICIPANTS 84 workers who were exposed to chromate for at least 1 year were chosen as the chromate exposed group, while 30 non-exposed individuals were us...

A statistical analysis of differential Doppler estimation is presented that includes the particular features found in aeroacoustic signals from ground vehicles, namely a sum-of-harmonics signal that is randomly scattered by the atmosphere. We use a physics-based statistical model for the scattering to derive the Cramér-Rao bound (CRB) on differential Doppler estimation as a function of the atmo...