نتایج جستجو برای: colorectal carcinoma
تعداد نتایج: 454376 فیلتر نتایج به سال:
AIM To explore the expression of Tiam1 gene in colorectal carcinoma and its correlation with tumor metastasis. METHODS Expressions of Tiam1 gene in 8 colorectal carcinoma cell lines were detected by reverse transcriptase-polymerase chain reaction. In vitro invasiveness was determined by means of Matrigel invasion assay. The correlation of Tiam1 expression with the invasive ability was also an...
Colorectal carcinoma has increasingly been reported to be associated with gut microbial dysbiosis. Bacteroides, Fusobacterium, Faecalibacterium, Blautia, etc., are microbes commonly colorectal carcinoma. Gut dysregulation secondary infectious, inflammatory, toxin exposure or change in dietary habits coupled the disruption of inner mucosal layer overlying luminal epithelium is hypothesized as in...
background: some recent studies reported human epidermal growth factor receptor (her-2/neu) as a marker that can be used in immunological studies of colorectal carcinoma for predicting the prognosis and the treatment. therefore, we aimed to investigate the frequency of her-2 expression in patients with colorectal cancer, and explore the relationship between clinicopathological prognostic factor...
Background: Colorectal carcinoma is a malignant epithelial tumor originating in the large bowel. More than 90% of colorectal carcinomas (CRC) are adenocarcinomas. This being graded morphologically at H&E stain histopathology as well-differentiated, moderately differentiated, and poorly differentiated. Aims Objectives: The aim this study to assess any association with different histopatholog...
Hepatocellular carcinoma (HCC) and colorectal cancer (CRC) are among the most common cancers across the world. Therefore, identifying the potential molecular mechanisms that promote HCC and CRC progression and metastasis are urgently needed. Spermidine/spermine N1-acetyltransferase (SSAT) is a catabolic enzyme that acetylates the high-order polyamines spermine and spermidine, thus decreasing th...
U pper urinary tract transitional cell carcinoma (UUTTCC) accounts for 5% of all urothelial carcinomas. Hereditary non-polyposis colorectal cancer (HNPCC) is an autosomal dominant syndrome predisposing to colorectal cancer that accounts for about 5% of all colorectal cancers. It is revealed by colorectal cancer (63%) or extracolonic cancers, most often of the endometrium (9%) or ovary, but some...
Background: Colorectal carcinoma is considering as a curable disease. Treatment of recurrent cases is hard and sometimes impossible. Evaluation of the rate and affecting factors of recurrence in each hospital would help to decreasing recurrent cases. The aim of this study is evaluation of the rate, clinical and pathologic features, and outcome of recurrent colorectal carcinoma in a referral tea...
Colorectal carcinoma is one of the most common causes of cancer-related death, worldwide. Recently, due to the introduction of novel imaging and therapeutic techniques, five-year survival of patients has increased. However, distant metastasis is still expected in half of the patients. Colorectal cancer tends to target the abdominal cavity, liver, lungs, and bones as the common sites of metastas...
Objectives:The aim of the study is to determine the histopathological features of primary colorectal cancers. Materials and methods: 102 patients with primary colorectal tumors diagnosed over a 5 year period studied histopathologically they were classified using the WHO classification of colorectal malignancies. primary gastrointestinal tumors Diagnosis. Result: Most of the colorectal tumors we...
Tumor angiogenesis shown by Microvessel Count (MVC) or Microvessel Density (MVD), is assessed by several studies as prognostic factor in some types of tumors, and also in colorectal carcinoma. This article is payed to correlation between clincopathologic factors and tumor angiogenesis. In this study, immunohistochemical techniques are used for vascular evaluation in specimens from twenty-nine c...
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