conclusions despite the fact that anesthesia in chronic liver disease is a scary and pretty challenging condition for every anesthesiologist, this hazard could be diminished by meticulous attention on optimizing the patient’s condition preoperatively and choosing appropriate anesthetic regimen and drugs in this setting. although there are paucity of statistics and investigations in this specifi...

conclusions pain management in patients with liver dysfunction is always challenging to physicians because of the adverse reactions of drugs, especially opioids. opioids should be used cautiously since they can cause sedation, constipation and sudden encephalopathy effects. since the clearance of these drugs in patients with hepatic insufficiency is decreased, the initial dose must be decreased...

background beta-2 microglobulin (b2m) is considered as a surrogate marker for middle molecule uremic toxins and a key component in dialysis-related amyloidosis. however, few studies have evaluated role of b2m in patients with chronic kidney disease (ckd). objectives the purpose of this study was to evaluate the association of plasma b2m level with some metabolic and cardiac performance factors ...

Introduction: The elderly represent a significant proportion of the populace and their mortality index is of public health significance. With dearth of vital registration, in-hospital based studies remains a desirable alternative. This study hopes to determine the epidemiologic pattern of elderly mortality with respect to sex, age, date and cause of death.  Methods: This is descriptive retrosp...

background: we aimed to determine the frequency of liver copper storage diseases in iranian children with cryptogenic chronic liver disease (cld). materials and methods: one-hundred and twenty children (52 girls, 70 boys; age range: 3 months-14 years) with cld who attended children's medical center in tehran, iran during the years 1997 through 1999, were enrolled. all viral, metabolic and autoi...

conclusions elevation of liver enzymes appears in 29 % obese children in a tertiary care centre. absolute alanine aminotransferase levels are significantly higher in obese than in overweight children. even obese children with normal liver enzymes show signs of fatty liver disease as demonstrated by liver enzymes at the upper limit of normal. results elevated alanine aminotransferase was observe...

Background: HCV chronic infection is a leading cause of end-stage liver disease and transplantation. The aim our study was to assess the benefits novel anti-HCV therapeutic approaches in obtaining viral clearance, reducing inflammation, regression fibrosis, improvement liver-related morbidity mortality.

background: celiac disease (cd) has been found in up to 10% of the patients presenting with unexplained abnormal liver function tests (lft). as there is no precise data from our country in this regard, we investigated the prevalence of cd in patients presenting with abnormal lft. methods: from 2003 to 2008, we measured iga anti-tissue transglutaminase (t-tg) antibody (with elisa technique) with...