ischaemic attacks or carotid disease was all very well, but did not answer the more relevant question: do patients with severe carotid disease and limb shaking transient ischaemic attacks have more impaired cerebrovascular reactivity than similar patients with 'con-ventional' transient ischaemic attacks (i.e. loss of function such as paralysis contralateral to severe carotid disease)? In this i...

The fracture of vulnerable carotid plaques is the major cause of cerebrovascular thromboembolic events such as strokes and ischemic attacks. To prevent this issue, carotid endarterectomy is the closely treatment for pathological plaques. The vulnerability is believed to be related to mechanical forces, vessel surface condition, cell activities and chemical environment. Several authors developpe...

Thirty nine cases of cerebellar infarct and haemorrhage were seen over a period of 3 years. Of these, 69% had no impairment of consciousness. Six cases had nystagmus and gait ataxia as their only abnormal signs. Small cerebellar strokes may present with only vertigo, unsteady gait, and unidirectional nystagmus, thus mimicking labyrinthine lesions. Care in managing vertigo attacks in patients wi...

Record Linkage in Studies of Cerebrovascular Disease in Oxford, England • Data collected by record linkage are used as a basis for an analysis of the burden of cerebrovascular diseases in a population of 340,000 in central England. Comparison with studies which use other methods in the United States and England indicate that for all cerebrovascular diseases together, and for subarachnoid hemorr...

BACKGROUND/OBJECTIVE Transient global amnesia (TGA) is a temporary amnestic syndrome characterized by lack of other focal neurological deficits. Cerebrovascular disease, migraine and seizures have been suggested as underlying mechanisms. TGA may be a risk factor for cerebrovascular or other neurological events. We studied the relation of TGA, vascular risk factors, brain magnetic resonance imag...

The results of recent multicenter studies of stroke prevention are encouraging. Carotid endarterectomy is highly beneficial for patients with recent transient ischemic attacks (TIA) or nondisabling stroke and ipsilateral high-grade stenosis (70-99%); ticlopidine significantly lowers the risk of stroke in patients with TIA or minor stroke compared with aspirin or placebo,' and coumadin and aspir...

background chlamydia pneumoniae has been linked with increased risk of cardiovascular diseases; however, data on stroke and cerebrovascular accidents are sparse. objectives the aim of this study was to determine the association between c. pneumoniae infection and ischemic stroke. patients and methods in a case-control study, 141 patients, admitted with ischemic stroke, were compared with gender...

In order to evaluate the pathogenetic importance of platelet aggregates in cerebrovascular disease, a platelet count ratio method was used to study 66 patients with transient ischemic attacks (TIAs). Thirty normal subjects and 22 patients without thromboembolic disorders were also included as controls. The mean platelet aggregate ratio of the TIA group was 0.75 +/- 0.03 SEM which was significan...

Project entitled “Cerebrovascular mediated subclinical brain injury – interaction between cardiovascular function, brain structure and cognitive functionstudy rationale, design and principal methods” is a cross-sectional study in a group of older individuals with no apparent symptoms of stroke, transient ischemic attacks or cognitive impairment. The primary aim of the projects is further our un...

A group of 143 male hypertensive patients with diastolic blood pressures (at the clinic) averaging between 115 and 129 mm Hg were randomly assigned to either active (hydrochlorothiazide plus reserpine plus hydralazine hydrochloride) or placebo treatment. Twenty-seven severe, complicating events developed in the placebotreated patients as compared to two in the active group. Four deaths occurred...