نتایج جستجو برای: caps

تعداد نتایج: 5878  

2015
N Rieber A Gavrilov L Hofer A Singh H Öz T Endres I Schäfer R Handgretinger D Hartl J Kümmerle-Deschner

Cryopyrin-associated periodic syndromes (CAPS) are characterized by recurrent episodes of systemic inflammation caused by mutations in the NLRP3 gene. Besides confirmed pathogenic NLRP3 mutations, patients with CAPS-like symptoms frequently show low penetrance variants in NLRP3. The disease relevance of these variants is inconsistent. In this study, we investigated if an inflammasome activation...

2017
Hiroshi ASHIGAI Yuta KOMANO Guanying WANG Yasuji KAWACHI Kazuko SUNAGA Reiko YAMAMOTO Ryoji TAKATA Mika MIYAKE Takaaki YANAI

Black currant (Ribes nigrum) has various beneficial properties for human health. In particular, polysaccharide from black currant was found to be an immunostimulating food ingredient and was reported to have antitumor activity in a mouse model. We named it cassis polysaccharide (CAPS). In a previous study, CAPS administration caused tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β) pro...

Journal: :Toxicological sciences : an official journal of the Society of Toxicology 2000
U P Kodavanti R Mebane A Ledbetter T Krantz J McGee M C Jackson L Walsh H Hilliard B Y Chen J Richards D L Costa

Chronic bronchitis may be considered a risk factor in particulate matter (PM)-induced morbidity. We hypothesized that a rat model of human bronchitis would be more susceptible to the pulmonary effects of concentrated ambient particles (CAPs) from Research Triangle Park, NC. Bronchitis was induced in male Sprague-Dawley rats (90-100 days of age) by exposure to 200 ppm sulfur dioxide (SO2), 6 h/d...

Journal: :Bioscience, biotechnology, and biochemistry 2007
Ryoji Takata Takaaki Yanai Reiko Yamamoto Tomonori Konno

A polysaccharide-rich substance isolated from black currant, named cassis polysaccharide (CAPS), was partially digested with beta-galactosidase from Aspergillus oryzae and its immunostimulatory activity was investigated. The in vitro cytokine-inducing effect of CAPS on RAW264 cells was gradually decreased along with lowering of the average MW of CAPS. In vivo, partially digested CAPS with a mea...

Journal: :Des. Codes Cryptography 2004
Yves Edel

We give some variants of a new construction for caps. As an application of these constructions we obtain a 1216–cap in PG(9, 3) a 6464–cap in PG(11, 3) and several caps in ternary affine spaces of larger dimension, which lead to better asymptotics than the caps constructed by Calderbank and Fishburn [1]. These asymptotic improvements become visible in dimensions as low as 62, whereas the bound ...

Journal: :Quarterly of Applied Mathematics 1988

Journal: :Bulletin of the Belgian Mathematical Society - Simon Stevin 2013

2017
Dorota M. Rowczenio Sónia Melo Gomes Juan I. Aróstegui Anna Mensa-Vilaro Ebun Omoyinmi Hadija Trojer Anna Baginska Alberto Baroja-Mazo Pablo Pelegrin Sinisa Savic Thirusha Lane Rene Williams Paul Brogan Helen J. Lachmann Philip N. Hawkins

Cryopyrin-associated periodic syndrome (CAPS) is caused by gain-of-function NLRP3 mutations. Recently, somatic NLRP3 mosaicism has been reported in some CAPS patients who were previously classified as "mutation-negative." We describe here the clinical and laboratory findings in eight British adult patients who presented with symptoms typical of CAPS other than an onset in mid-late adulthood. Al...

Journal: :Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology 2011
Megumu K Saito

Cryopyrin-associated periodic syndrome (CAPS) is an autoinflammatory syndrome caused by heterozygous mutations of NLRP3 gene. CAPS consists of three phenotypically similar but distinct syndromes: familial cold autoinflammatory syndrome (FCAS), Muckle-Wells syndrome and CINCA syndrome. Among them, FCAS shows the mildest phenotype while CINCA is the severest. Common symptoms include sporadic or c...

1998
Mark Broadie Jerome Detemple

Thi s a r t i c l e addres se s the p rob l em o f va lu ing Amer i can ca l l op t i ons w i th caps on d i v idendpaying assets . Since early exercise is al lowed, the valuat ion problem requires the determinat ion of opt imal exercise pol icies . Options with two t ypes o f caps a re ana ly zed cons tan t caps and caps with a constant growth rate. For constant caps, it is optimal to exercise...

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