Bupropion is an antidepressant with excellent tolerability and fe to side f!ffects or drug interactions. These characteristics suite it ioellfo r use both in the elderly and in the medically ill. Huwever, early reports ofseirures with bupropion therapy in patients with bulimia limited its use. The pharmacology, tdJicacy, toxicity, and side dftct profile qfboth the immediate release (IR) and the...

Objective Several studies have suggested the efficacy of bupropion and escitalopram on reducing the excessive internet game play. We hypothesized that both bupropion and escitalopram would be effective on reducing the severity of depressive symptoms and internet gaming disorder (IGD) symptoms in patients with both major depressive disorder and IGD. However, the changes in brain connectivity bet...

Although the exact mechanism that makes bupropion hydrochloride (Zyban) effective as a smoking cessation aid has not been fully elucidated, studies have found that bupropion and nicotine share behavioural and neurophysiological properties suggesting that bupropion might serve as a substitute for nicotine. In fact, bupropion prompts nicotine-appropriate responding in operant and Pavlovian drug d...

Bupropion hydrochloride (HCI) is an antidepressant that acts as a norepinephrine and dopamine reuptake inhibitor and has three different dosage forms including immediate release (IR), sustained release (SR), and extended release (ER). Despite its relatively safe side effect profile bupropion may cause several side effects. Here, we aimed to report a case with major depression using extended rel...

attention-deficit/hyperactivity disorder is one of the most common mental disorders in childhood, and it continues to adulthood without proper treatment. stimulants have been used in the treatment of attention-deficit/hyperactivity disorder (adhd) for many years, and the efficacy of methylphenidate in the treatment of adults with adhd has been proven to be acceptable according to meta-analysis ...

conclusions these results provide empirical support for conducting a further study on comparing different add-on strategies for treating drug-induced sd. background antidepressant-induced sexual dysfunction (sd) is a common problem, associated with a significant risk of non-adherence. selective serotonin reuptake inhibitors (ssris) are associated with a substantial risk of sd. only 10 % of pati...

Bupropion is a dopamine/norepinephrine reuptake inhibitor and considered to carry a much lower risk of inducing mood shift compared with other antidepressants. We described here a patient who experienced the first episode of mania with psychotic features after escalating the dose of bupropion in the treatment of major depression disorder. Miss C is a 40-year-old female, who was diagnosed major ...

INTRODUCTION Bupropion is used to help people stop smoking. This drug can cause visual alterations but, up to now, its use was not associated with anisocoria. CASE REPORT A 40 year-old woman with a personal history of migraines, presented with monocular mydriasis during treatment with bupropion. Both pupils dilated equally after a 5% cocaine test, and constricted equally after a 0.025% Piloca...

BACKGROUND AND OBJECTIVE Despite animal studies having shown a generalisation of the bupropion cue to cocaine, this drug has been used in cocaine abuse with mixed results. We here aimed at describing two cases which contradict current knowledge. CASE REPORTS We describe two cases of former cocaine abusers who reported a cocaine-like sensation upon taking bupropion. Bupropion improved patients...

Serotonergic medications are used for the prevention and treatment of depression during pregnancy. Selective serotonin reuptake inhibitors serotonin-norepinephrine (SNRIs) can cause poor neonatal adaptation, which has been attributed to withdrawal versus toxicity. Bupropion, a norepinephrine-dopamine inhibitor, is often as an adjunctive agent selective or SNRIs refractory depression. Quetiapine...