PURPOSE To examine whether the bronchodilatory effect of atropine differs in the evening from the morning. METHODS Thirteen adult healthy volunteers with no oral medication intake were studied. At 1600, peak expiratory flow (PEF) was measured three times, and the highest value recorded. Subsequently, the volunteer received 0.01 mg(-1) x kg(-1) atropine im, and the PEF was measured every 30 mi...

Woodfordia fruticosa dried flower (WF-EE). WF-EE exhibited significant and dose dependent bronchoprotective, bronchodilatory and antiinflammatory effect. WF-EE at 200 mg/kg prolonged the latent period and exhibited protection against experimental asthma induced by the combination of histamine and acetylcholine aerosol in guinea pigs. WF-EE (1 mg/ml) exhibited 100 % bronchodilation (complete bro...

  In this study we investigated the bronchodilatory and anticholinergic effects of the aqueous extract (AE), brewed extract (BE) and ethanol extract (EE) of Polygonum avicular in comparison with saline (S) on isolated tracheal chains of the guinea pig. Due to the probable confounding effect of ethanol in the EE, the effects of this extract were also compared with 96 % ethanol. None of the plant...

Objective: Black cumin or Nigella sativa (N. sativa) seed has been widely used traditionally as a medicinal natural product because of its therapeutic effects. In this review, the medicinal properties of N. sativa as a healing remedy for the treatment of respiratory and allergic diseases, were evaluated. Material and Methods: Ke...

backgrounds: all of long-acting β2-agonists are beneficial in maintenance treatment of asthma but their use in relieving acute asthma attacks is not well known. the aim of this study was to compare rapid bronchodilatory effects of salmeterol and formoterol in patient with moderate to severe asthma. methods: it was a randomized, double blind, cross-over study on 60 patients with moderate to seve...