Tinidazole is a broad spectrum antiprotozoal agent having bitter taste. The present study concerns to mask the bitter taste of tinidazole as an orally disintegrating tablet (ODT) using Indion 294 and Indion 204 (ion exchange resin) as a taste masking agent. In first method, 1:1, 1:2 and1:3 ratios of drug and resin were stirred for six hour. Percent drug losses were found to be on higher side in...

Abstract Considering that vaginal delivery is a painful process, the present study investigated the effects of Citrus aurantium on the severity of first-stage labor pain in primiparous women. This study was a randomized clinical trial conducted with 126 eligible primiparous patients. The pain severity of patients was measured at the time of enrolling in the study. In the intervention group, (ar...

Abstract Considering that vaginal delivery is a painful process, the present study investigated the effects of Citrus aurantium on the severity of first-stage labor pain in primiparous women. This study was a randomized clinical trial conducted with 126 eligible primiparous patients. The pain severity of patients was measured at the time of enrolling in the study. In the intervention group, (ar...

OBJECTIVE To understand the available evidence of how children and adults differ in their preferences for flavours that may be used in tobacco products. DATA SOURCES A total of 474 articles published between 1931 and August 2015 were retrieved through searches conducted in PubMed, EMBASE, Web of Science and PsycINFO. STUDY SELECTION AND EXTRACTION A 2-phase relevancy review process resulted...

background : the main objective of this study was to design, formulate and evaluate the physicochemical properties of 500 mg acetaminophen effervescent tablets, in order to accelerate its analgesic and antipyretic effects in patients with pill swallowing problems. methods : formulations with 500 mg of acetaminophen were prepared with effervescent bases including tartaric acid, citric acid, sodi...