variety of positive as well as negative regulatory signals are provided by antigen presenting cell in particular by dendritic cells. in this research, we studied the capacity of dendritic cells to expand antigen-specific t regulatory cells.we also investigated the role of tgf-beta in induction inhibitory functions of dendritic cells in mixed leukocyte reactions. dendritic cells were generated f...

The human amniotic membrane known as the innermost single epithelial-covered layer provides many applications such as applicable anti-inflammatory and anti-cancer effects. These immunomodulatory effects belongs to the epithelial cells, a type of epiblast-derived fetal stem cells which currently used for regenerative medicine and transplantation. These cells are collected by author-prepared faci...

Background: The thyroid gland absorbs nearly all the iodine in the blood, independently of its isotopic composition. When a large enough activity of radioactive iodine like 131I, 132I, 133I is taken into the body, it can destroy the healthy thyroid gland cells as well as the cancer’s cells. In fact, as it is well known, some isotopes of iodine are used not only for acquiring thyroid image...

Alzheimer’s disease is a common neurodegenerative disease. Microglia induces oxidative stress in the brain for engulfing bacteria and viruses. The accumulating data indicate that apoptosis are two main actors induction of microglia activation-induced Disease. Oxidative one many triggers activate transient receptor potential melastatin 2 (TRPM2) channel. Glutathione (GSH) cytosolic antioxidant m...

background: the thyroid gland absorbs nearly all the iodine in the blood, independently of its isotopic composition. when a large enough activity of radioactive iodine like 131i, 132i, 133i is taken into the body, it can destroy the healthy thyroid gland cells as well as the cancer’s cells. in fact, as it is well known, some isotopes of iodine are used not only for acquiring thyroid images but ...

Introduction: Cancer is, in essence, a genetic disease and is the second leading cause of death globally. Fortunately, many common types of cancer are treatable if detected early and of course there are many medications and treatments available today. Among the new methods to treat cancer, radiotherapy seems to be hopeful in patients with malignancies. This work investigates th...