نتایج جستجو برای: bcg scar
تعداد نتایج: 21757 فیلتر نتایج به سال:
OBJECTIVE To study local response to BCG vaccination in twin babies and find out the effect of zygosity andchorionicity on BCG uptake. DESIGN Analytical observational study. SETTING Tertiary hospital. METHODS Twin pairs born in the hospital were evaluated for zygosity and chorionicity. BCG vaccination was given within 48 hours of birth to babies >/=33 weeks of gestation and birth weight >...
BACKGROUND: The protection, which some BCG vaccines could confer against the development of tuberculosis (TB) in childhood, might be indirectly reflected by the subsequent development of BCG immune response. The objectives of the study were to examine effectiveness and possible differences of post-vaccination reaction to a lyophilized BCG at different age groups and to evaluate its protection a...
Tuberculosis (TB) is the most common cause of death in children. Prevention TB through Bacille Calmette–Guérin (BCG) vaccination an action to produce immunity against disease. After vaccination, a scar forms from boil, which indicates successful vaccination. This study aims determine factors associated with BCG Scar pediatric patients. A cross-sectional design was conducted at Pisangan and East...
While BCG vaccine protects against severe tuberculosis (TB) in children, its effect against adult TB is questionable. Furthermore, it is not known if HIV co-infection modifies the effect of BCG. Among 352 pairs of Tanzanian TB cases and matched controls, the BCG scar was associated with a reduced risk of TB (OR 0.3, 95% CI 0.2 to 0.7, p=0.005), irrespective of HIV status (interaction, p=0.623)....
BACKGROUND The only available vaccine that could be potentially beneficial against mycobacterial diseases contains live attenuated bovine tuberculosis bacillus (Mycobacterium bovis) also called Bacillus Calmette-Guérin (BCG). Even though the BCG vaccine is still widely used, results on its effectiveness in preventing mycobacterial diseases are partially contradictory, especially regarding Burul...
BACKGROUND It is still a matter of debate whether there is an association between infection with Mycobacterium tuberculosis (M. tuberculosis) and allergy. Previously, we have shown higher levels of specific IgE to different inhalant allergens and total IgE in tuberculosis (TB) patients compared to controls. The objectives of this study were to evaluate a possible change in allergic sensitisatio...
BACKGROUND Globally, BCG vaccination varies in efficacy and has some non-specific protective effects. Previous studies comparing BCG strains have been small-scale, with few or no immunological outcomes and have compared TB-specific responses only. We aimed to evaluate both specific and non-specific immune responses to different strains of BCG within a large infant cohort and to evaluate further...
Timing and dose of BCG vaccination in infants as assessed by postvaccination tuberculin sensitivity.
Tuberculosis is an important public health problem in developing countries and BCG plays an important role in preventing serious form of the disease in children. BCG induced tuberculin sensitivity is a quantitative characteristic and has been used to compare vaccine efficacy. The standard dose of BCG vaccine is 0.1mg in 1 ml though manufacturers of certain strains of BCG, i.e., Copenhagen 1331 ...
BACKGROUND Vitamin A supplementation (VAS) at birth has been associated with decreased mortality in Asia. Bacille Calmette-Guérin (BCG) vaccine is given at birth in tuberculosis-endemic countries. Previous studies suggest that VAS may influence the immune response to vaccines. OBJECTIVE Our objective was to examine whether VAS influences the immune response to simultaneously administered BCG ...
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