نتایج جستجو برای: anaesthetics

تعداد نتایج: 2374  

Journal: :Asian journal of andrology 2013
Jia-Dong Xia You-Feng Han Liu-Hua Zhou Yun Chen Yu-Tian Dai

To assess the efficacy and safety of local anaesthetics for premature ejaculation (PE), a systematic review of the literature was performed using the Cochrane Library, PUBMED and EMBASE. We screened and retrieved the randomized controlled trials on the treatment of PE with local anaesthetics. End points included intravaginal ejaculation latency time (IELT), patient-reported outcome assessments ...

2005
Benedicte Mengel Maria Christiansen

The mechanism by which anaesthetics work is much discussed. The most prevalent view is that anaesthetics bind to ligand gated ion channels thereby restricting their function. Another view is that anaesthetics interact directly with the cell membrane, changing properties of the membrane leading to a conformational change in the membrane proteins which causes anaesthesia. In this thesis we will i...

Journal: :British journal of anaesthesia 1997
T Andoh T J Blanck I Nikonorov E Recio-Pinto

Volatile anaesthetics are known to increase leakage of calcium from the light fraction of skeletal sarcoplasmic reticulum (L-SR) which has no calcium release channels. To explore the role of the lipid environment, we have examined the effect of volatile anaesthetics on calcium conductance (gCa) of lipid membranes. Planar lipid bilayers were formed with a mixture of synthetic phospholipids and c...

2010
K. Maurer J. Wacker N. Vastani B. Seifert D. R. Spahn

Key points † Intraoperative neuromonitoring can be affected by specific general anaesthetics. † Changes in axonal excitability of primary sensory afferents with propofol and sevoflurane were investigated using threshold tracking technique. † Both anaesthetics similarly affected nerve excitability to a small but significant extent. † Possible mechanisms include direct anaesthetic effects on neur...

Journal: :British journal of anaesthesia 2011
J M van Schalkwyk D Lowes C Frampton A F Merry

BACKGROUND Numerous studies have shown smoothing and inaccuracies in handwritten anaesthetic records, but the clinical relevance of these findings is unclear. We therefore sought to determine whether the behaviour of anaesthetists differed in assessing anaesthetic records re-synthesized from either handwritten or automated records. METHODS In a recent New Zealand study (ACTRN12608000068369), ...

Journal: :British journal of anaesthesia 1999
T Langbein H Sonntag D Trapp A Hoffmann W Malms E P Röth V Mörs R Zellner

The atmospheric lifetimes of the halogenated anaesthetics halothane, enflurane, isoflurane, desflurane and sevoflurane with respect to reaction with the hydroxyl radical (OH.) and UV photolysis have been determined from observations of OH. reaction kinetics and UV absorption spectra. Rate coefficients for the reaction with OH radicals for all halogenated anaesthetics investigated ranged from 0....

Journal: :Canadian Anaesthetists' Society journal 1986
B G Covino

In general, the cardiovascular system is more resistant to the toxic actions of local anaesthetics than is the central nervous system. However, if sufficient doses and blood levels of local anaesthetics are achieved, signs of profound cardiovascular depression may be observed. Differences exist between local anaesthetics in terms of their relative potential for cardiotoxicity. The CC/CNS ratio ...

2015
Bogusław Sobolewski Paweł Doman Tomasz Stetkiewicz Przemysław Oszukowski Piotr Woźniak

Gynaecologists often use local anaesthetics in their medical practice. Some concomitant diseases during the menopausal period may cause problems during the qualification of postmenopausal women for general anaesthesia in gynaecological surgery. Many authors suggest the application of local analgesia for particular kinds of gynaecological surgery procedures performed on postmenopausal women, tak...

Journal: :British Journal of Anaesthesia 1966

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