A previous study (15) has shown tha t transplantable mouse tumors differ in their capacity to grow progressively in rats pretreated with lyophilized mouse tumor tissue. An inverse correlation was found between the degree of strain specificity of tumors in mice and their transplantability to Pretreated rats. The present study deals with the correlation found between the transplantability of mous...

Reliability of the Widal tube agglutination test has been the subject of many controversies over the years. This study was performed to assess the effect of certain modifications on the performance of Widal test in a novel microplate assay. Sera from 37 patients (21 males; 16 females) (mean age 28 +/- 7 years) were tested in the Immunology Unit at King Khalid University Hospital, Riyadh. Among ...

The phenomenon of in vitro platelet clumping and consequent pseudothrombocytopenia in the presence of EDTA was studied in the plasmas and sera of three patients. A heterogeneity was identified among these platelet agglutinins. lgG agglutinins present in two patients recognized antigens that were present when EDTA was added to platelets. This effect of EDTA did not appear to be mediated by calci...

The phenomenon of in vitro platelet clumping and consequent pseudothrombocytopenia in the presence of EDTA was studied in the plasmas and sera of three patients. A heterogeneity was identified among these platelet agglutinins. lgG agglutinins present in two patients recognized antigens that were present when EDTA was added to platelets. This effect of EDTA did not appear to be mediated by calci...

Eleven haemophiliac boys infected with HIV were screened for irregular red cell antibodies and were compared with nine haemophiliac boys who did not have antibodies to HIV. Seven (64%) of the children who had antibodies to HIV also had cold agglutinins, mostly of anti-I specificity, compared with one (11%) of those who did not have antibodies to HIV. The children with antibodies to HIV and cold...

The red cells of patients with chronic hemolytic anemia due to cold agglutinins are agglutinated by antiglobulin serum in a nongamma reaction due to the coating of beta-globulins, C'4 and C'3. The red cells of such patients are abnormally resistant to C' hemolysis by cold agglutinin. Normal red cells can be made equally resistant to C' hemolysis by incubation with cold agglutinin and normal ser...

Species-specific binding between the flagellar surfaces of mating types plus and minus (mt+ and mt-) gametes of Chlamydomonas eugametos is mediated by mating type-specific agglutinins. Their interaction triggers several mating responses that are necessary for cell fusion, such as flagellar twitching, flagellar tip activation, redistribution of agglutinin molecules to the flagellar tip (tipping)...

The importance of blood transfusion in stimulating the production of most leuko-agglutinins is established beyond all doubt. Among 60 leuko-agglutinating sera studied by Dausset, 90 per cent were from patients who had received multiple (average of 22) transfusions. Brittingham, Andre et al. and Payne also noted a high degree of correlation. Other than leuko-agglutinins, various types of homolog...

1. Protective substances and agglutinins were not demonstrated in the blood of patients with pneumonia untreated with serum before the fall in the temperature by crisis or lysis. 2. Protective substances and agglutinins were frequently demonstrated in serum treated patients during the course of the disease. 3. Protective substances and agglutinins were usually present at the time of the tempera...

The incidence of brucellosis in the human population of England and Wales is still not accurately known, although estimates have been made (Wilson, 1932; Dalrymple-Champneys, 1950). Few persons who acquire Br. abortus develop any obvious clinical disease, but the existence of Br. abortus agglutinins in blood sera indicates past exposure to the organism. A survey of human and animal brucellosis ...