objective: in this study, we investigated the combined effect of 2-methoxyestradiol (2me2) and 60co on the cytogenetic damage of iododeoxyuridine (iudr) in the spheroid model of u87mg glioblastoma cancer cell lines by alkaline comet assay. materials and methods: u87mg cells were cultured as spheroids with diameters of 350 μm. as control, the spheroids of one plate were not treated. other cultur...

---------------------------------------------------------------------***--------------------------------------------------------------------Abstract The dose distribution in irradiation room and the dose rate at each dwell position of 60Co irradiator SVST-Co-60/B have been calculated using MCNP code. The calculated results are useful information to estimate radiation safety and design irradiato...

In earlier combination chemotherapy regimens for childhood acute lymphocytic leukemia, nervous system leukemia terminated complete remission in over half the patients in a median time of 11 months. In the present study, cranial radiation (2400 R, 60Co) and intrathecal methotrexate given early in remission were added to combination chemotherapy in an attempt to prevent or delay central nervous s...

programs. 1 General coincidence summing problems and specific coincidence summing problems encountered when measuring these two radionuclides on filter papers were discussed in the last issue? In order to perform accurate measurements of 134CS and 60Co in liquid samples using Marinelli beakers, coincidence summing effects should be investigated. Liquid samples of 134Cs and 60Co were prepared in...

Adaptive responses were observed using the micronucleus frequency in bullfrog tadpoles. In tanks in which control tadpoles were placed in contact with tadpoles that were previously housed in tritiated water (3.0× 104 Bq/L), the cells from all animals responded as though they were “adapted”. This suggests that direct exposure to 3.0× 104 Bq/L tritium contributes to an increased resistance to a h...

The cancer of oral cavity is related to lesions of mucous membrane of tongue and gum that can be treated with radiation therapy. A lateral photon field can be used to treat this kind of tumor, which has a side-effect on normal tissue in the opposite side of the oral cavity. In this study the dosimetric effect of the various shields in oral cavity is evaluated. In this study, a special phantom s...

Cobalt is an integral part of the vitamin Bl2 complex and an important cofactor in enzyme systems (Lowman et al. 1971; Reichle et al. 1970). It is, therefore, an element whose cycle in oceanic ecosystems is of interest. The artificial radionuclide cobalt-60 (60CO) has been observed in the livers of albacore, (Thunnus alalunga Bonnaterre) collected off the west coast of North America, Washington...