A new method of constructing optimum constant weight codes over F2 based on a generalized (u,u + v) construction [1]∼ [3] is presented. We present a new method of constructing superimposed code C (h1,h2,··· ,hI) (s1,s2,··· ,sI) bound. and presented a large class of optimum constant weight codes over F2 that meet the bound due to Brouwer and Verhoeff [4], which will be referred to as BV . We pre...

Using the formula periodic table for benzenoids (Table PAH6 = Table 1 in [4]) and the excised internal structure concept, several new strictly peri-condensed series possessing an identical number of isomers have been identified [5]. Strictly peri-condensed benzenoids have the property that the graph spanned by their internal carbon vertices (i.e., their excised internal structure) is connected....

The murine monoclonal antibody (MAb) 18B7 [immunoglobulin G1(kappa)] is in preclinical development for treatment of Cryptococcus neoformans infections. In anticipation of its use in humans, we defined the serological and biological properties of MAb 18B7 in detail. Structural comparison to the related protective MAb 2H1 revealed conservation of the antigen binding site despite several amino aci...

Our work reports in detail the results of systematic large-scale theoretical investigations of the glycosaminoglycan building units 1-OMe DeltaIdoA-2SNa2 (1; 2H1 and 1H2 forms), 1-OMe GlcN-S6SNa2 (2), 1,4-DiOMe GlcNa (3), 1,4-DiOMe GlcN-S3S6SNa3 (4), 1,4-DiOMe IdoA-2SNa2 (5; 4C1, 1C4, and 2So conformations), and 1,4-DiOMe GlcN-S6SNa2 (6) at the BP86/TZ2P level of the density functional theory. ...

Belief networks, also called Bayesian networks, are a form of artificial intelligence that incorporate uncertainty through probability theory and conditional dependence. Variables are graphically represented by nodes whereas conditional dependence relationships between the variables are represented by arrows. A belief network is developed by first defining the variables in the domain and the re...

Skimmia laureola Hook (Rutaceae) is found in Kashmir and in the mountains of Northern Pakistan and is used in folklore medicine for the treatment of various ailments [1 – 3]. The quinoline alkaloids of this plant have demonstrated antifungal and immunomodulating properties [4, 5]. The ethanolic extracts of the aerial parts of S. laureola are active against the animal pathogen Microsporium canis...

Hexabromocyclododecane (HBCD) and polybrominated diphenyl ethers (PBDEs) are additive flame retardants used in a wide range of consumer products. Both compounds have been detected in free-living avian species, but toxicological and molecular end points of exposure are limited. An in vitro approach was used to compare concentration-dependent effects of HBCD and the commercial penta-brominated di...

Heparin is a polydisperse sulphated copolymer consisting mostly of 1-->4 linked glucosamine and uronic acid residues, i.e. 2-deoxy-2-sulphamido-D-glucopyranose 6-sulphate and L-idopyranosyluronic acid 2-sulphate. 13C NMR has been used to study the interactions of heparinase-derived and purified heparin disaccharide with N- and C-terminally-blocked tripeptides GRG and GKG. Titration of the disac...