The maternal diet is an important determinant of glutathione-related metabolism in rats. Glutathione (GSH) may play a major role in the detoxification of sulfur dioxide (SO2) within the lungs. The effects of fetal exposure to a low protein maternal diet upon later susceptibility to pulmonary injury induced by chronic SO2 exposure were evaluated in young adult rats. Pregnant rats were fed purifi...

background: the pattern of drug abuse in iran has dramatically changed in recent years, turning from the traditional opioids [opium, opium dross, and refined opium dross (shireh)] into drugs with newer forms. the present study is aimed at investigating the frequency of pathological changes in the lungs of bodies with positive postmortem toxicology results for narcotics and psychotropic substanc...

INTRODUCTION The mechanisms of ventilator-induced lung injury (VILI), including the role of MAP kinases, are frequently studied in different mouse strains. A useful model for such studies is the isolated perfused mouse lung. As a further development we present the one-lung method that permits to continue perfusion and ventilation of the right lung after removal of the left lung. This method was...

Selon les données récentes des comptes nationaux, le rythme de croissance l’économie belge s’est sensiblement raffermi en début d’année, PIB national ayant augmenté 0,5% entre décembre 2022 et mars 2023. Il ressort par ailleurs l’évolution récente plusieurs indicateurs conjoncturels que a progressé au même soutenu cours du 2ème trimestre.
 Malgré repli important prix l’énergie, la ne devra...

Neural crest cells (NCCs) can adopt different neuronal fates. In NCCs, neurogenin-2 promotes sensory specification but does not specify different subclasses of sensory neurons. Understanding the gene cascades that direct Trk gene activation may reveal mechanisms generating sensory diversity, because different Trks are expressed in different sensory neuron subpopulations. Here we show in chick a...

Trends in Abortion Attitudes The GSS has carefully maintained the same wording and sequence of questions from year to year to avoid introducing context changes into the time series.* Respondents are asked whether a woman should be able to obtain a legal abortion for a series of reasons, beginning with “if there is a strong chance of defect in the baby” and ending with “if the woman wants it for...

The local intrapulmonary role of tumor necrosis factor alpha (TNF-alpha) in a protective host response during acute and chronic infection with Mycobacterium tuberculosis is incompletely understood. To directly assess its role in the intrapulmonary immune response, we compared the responses of transgenic mice with a local pulmonary blockade of TNF-alpha (SPCTNFRIIFc mice) to mice with globally i...

To capture the possible genotypic and phenotypic differences of the 2009 influenza A virus H1N1 pandemic (H1N1pdm) strains circulating in adult hospitalized patients, we isolated and sequenced nine H1N1pdm viruses from patients hospitalized during 2009-2010 with severe influenza pneumonia in Kentucky. Each viral isolate was characterized in mice along with two additional H1N1 pandemic strains a...