In conscious, chronically instrumented rats we examined 1) renal tubular functional changes involved in lipopolysaccharide (LPS)-induced acute renal failure; 2) the effects of LPS on the expression of selected renal tubular water and sodium transporters; and 3) effects of milrinone, a phosphodiesterase type 3 (PDE3) inhibitor, and Ro-20-1724, a PDE4 inhibitor, on LPS-induced changes in renal fu...

This study tested the hypothesis that regulation of 3',5'-cAMP levels in the kidney vasculature is abnormal in spontaneously hypertensive rats. In isolated, perfused kidneys from adult rats (16 weeks of age), isoproterenol similarly increased renal venous 3',5'-cAMP secretion from kidneys of hypertensive versus normotensive Wistar-Kyoto rats. However, a broad-spectrum phosphodiesterase inhibito...

Affiliation 6 Department of Physiology, Kyoto Prefectural University of Medicine, 602-8566, 7 Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto, Japan. 8 9 Correspondence is addressed to Hiroshi Yamada 10 Contact information 11 National Center of Neurology and Psychiatry 12 4-1-1 Ogawa-Higashi, Kodaira, Tokyo 187-8502, Japan 13 TEL: +81-42-346-1724 (Extension:5271) 14 Fax: +81-42-346-1754 15 Email: h-yam...

Page 1724, column 2, section 2.4, paragraph 2, lines 25–31: The following sentence, which previously read: To verify the effectiveness of BT on a balance outcome measures, we computed the within-subject standardized mean difference [SMDws = ([mean pre-value mean post-value]/SD pre-value)] and the between-subject standardized mean difference [SMDbs = ([mean post-value intervention group mean pos...