نتایج جستجو برای: 16a
تعداد نتایج: 367 فیلتر نتایج به سال:
Four new saponins, 3-O-[beta-D-glucopyranosyl(1-->3)-alpha-L-arabinopyranosyl]-16a lpha-hydroxyoleanolic acid 28-O-beta-D-glucopyranosyl ester (called aralia-saponin I), 3-O-[beta-D-glucopyranosyl(1-->3)-alpha-L-arabinopyranosyl]-16a lpha-hydroxyhederagenin 28-O-beta-D-glucopyranosyl ester (aralia-saponin II), 3-O-[beta-D-glucopyranosyl(1-->3)-beta-D-glucopyranosyl(1-->3)-alpha-L-+ ++arabinopyr...
The design and synthesis of a small library of pyrrolidine iminocyclitol inhibitors with a structural similarity to 1,4-dideoxy-1,4-imino-D-arabitol (DAB-1) is reported. This library was specifically designed to gain a better insight into the mechanism of inhibition of glycosidases by polyhydroxylated pyrrolidines or iminocyclitols. Pyrrolidine-3,4-diol 15a and pyrrolidine-3,4-diol diacetate 15...
Abstract Novel tri-and tetra-cyclic compounds based on the thiadiazolopyrimidine ring system were synthesized, and their antimicrobial activity was estimated. The obtained results evidenced substantial efficiencies of pyrano-thiadiazolopyrimidine 8a–b 9a–b toward two strains gram-positive bacteria ( S. aureus B. cereus ). Besides, tetracyclic pyrazolopyrimido-thiadiazolopyrimidine derivatives 1...
Glycopeptides bearing Tn epitopes are emerging targets for cancer diagnosis and immunotherapy. In this study, we analyzed membrane proteins containing O-glycosylated tandem repeat (TR) sequences in lung cancer patients of different types and stages, using gene microarray data in public domain. The expression of Tn and glycopeptide epitopes on the surface of lung cancer cell lines were studied b...
Sugars with heteroatoms other than oxygen have attained considerable importance in glycobiology and in drug design since they are often more stable in blood plasma due to their resistance to enzymes, such as glycosidases, phosphorylases and glycosyltransferases. The replacement of oxygen atoms in sugars with sulfur forms thio-sugars, which are potentially useful for the treatment of diabetes an...
IEEE 802.16 specifies an air interface for PMP systems operating in the 10 – 66 GHz frequency range. IEEE 802.16a amends 802.16 by adding the specification for an air interface for both PMP and mesh systems operating in the 2 – 11 GHz frequency range. There are a number of options for different applications and to cater for the wide frequency range addressed in the standard. A mesh option using...
Definition. Let G and H be groups. Their direct product is the group G×H defined as follows. As a set G×H = {(g, h) : g ∈ G, h ∈ H} is just the usual Cartesian product of G and H (the set of ordered pairs where the first component lies in G and the second component lies in H). The group operation on G×H is defined by the formula (g1, h1)(g2, h2) = (g1g2, h1h2) for all g1, g2 ∈ G and h1, h2 ∈ H....
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