Complexing a drug may alter the rate and extent of drug absorption. The complex formation is very well applied in the administration of poorly water-soluble drugs. The drugs selected for the study are cyclooxygenase-2 inhibitors, are potent anti-infl ammatory drugs with very low water solubility. The water solubility of these drugs was enhanced by complexing with β-cyclodextrin. In vitro absorp...

Intestinal cell proliferation and cell production is best quantified by measuring the rate of accumulation of vincristine arrested metaphases in microdissected intestinal crypts to determine the crypt cell production rate (CCPR). Studies of intestinal adaptation could be much more informative if a valid measure of intestinal function could also be included. One such method is the water absorpti...

The differences in water absorption properties were investigated among three types of flat pastas (LT: pasta dried at low temperature 50°C for 20 hours ; HT: pasta dried at high temperature 70°C for 11 hours; VHT: pasta dried at very high temperature 85°C for 4 hours). Pastas were soaked at different temperatures and for different times in a thermostatic bath to investigate moisture distributio...

1. Glucose absorption, water absorption and dipeptide hydrolase activities have been determined in isolated rat small intestine at 1, 3, 5 and 21 days after a single intraperitoneal injection of 5-fluorouracil. 2. Absorption rates and enzyme activities were elevated 1 day after treatment, but were reduced to 40% of control values at 3 and 5 days. Changes were seen regardless of whether absorpti...

Glycol ethers are solvents widely used alone and as mixtures in industrial and household products. Some glycol ethers have been shown to have a range of toxic effects in humans following absorption and metabolism to their aldehyde and acid metabolites. This study assessed the influence of water mixtures on the dermal absorption of butoxyethanol and ethoxyethanol in vitro through human skin. But...

Three sheep fitted with a ruminal cannula and an abomasal catheter were used to study water kinetics and absorption of VFA infused continuously into the rumen. The effects of changing VFA concentrations in the rumen by shifting VFA infusion rates were investigated in an experiment with a 3 x 3 Latin square design. On experimental days, the animals received the basal infusion rate of VFA (271 mm...

It is well known that low soil temperatures decrease the absorptionl of water by plants. Many years ago SACHS (24) reported that tobacco and gourd plants growing in moist soil under conditions favoring a low rate of transpiration wilted when the soil was cooled to 30 to 50 C., but recovered when the soil was warmed to 120 to 180 C. Cabbage and turnips were less affected, absorbing enough water ...

The influence of adrenergic drugs and electrical stimulation of the splanchnic nerves on concentrating function and motility in the feline gall bladder and on heptic bile secretion have been studied in vivo. It was found that electrical stimulation of the splanchnic nerves and adrenergic alpha-receptor stimulation increase the rate of net water absorption from the gall bladder lumen. Adrenergic...

An important application of starch grafted with copolymers from unsaturated organic acids is the use as water absorbent. Although much research has been published in recent years, the kinetics of water absorption and the swelling behavior of starch based superabsorbents are relatively unexplored. Also, water retention under mechanical strain is usually not reported. Cassava starch was used sinc...

Superabsorbent polymers (SAPs) can absorb a large amount of water and find broad applications in various industries. There are many reports on the synthesis structural modification techniques to improve absorption property SAPs. However, we see few studies comparison integration these techniques. In this study, three structurally modified SAPs were synthesized evaluated for effects surface cros...