Abdominal aortic aneurysm (AAA) is a vascular condition that causes permanent dilation of the abdominal aorta, which can lead to death due to aortic rupture. The only treatment for AAA is surgical repair, and there is no current drug treatment for AAA. Aortic inflammation, vascular smooth muscle cell apoptosis, angiogenesis, oxidative stress and vascular remodeling are implicated in AAA pathoge...

IN CEREBRAL vascular disease, difficulties in pathogenesis, diagnosis, and treatment are at present the rule rather than the exception. This discomforting situation is due to our rather limited knowledge concerning the etiology and pathogenesis of vascular disease in general, to the relative inaccessibility of the human brain, and to the resultant paucity of rational therapeutic modalities. It ...

In this review, the aim is to discuss pathological development of vascular calcification including a brief description arterial wall structure and function, atherosclerosis, highlighting normal physiological with particular emphasis on their common characteristics, critically review recent findings implicating role smooth muscle cells in pathogenesis process microRNAs regulation these phenotype...