Polycyclic aromatichydrocarbons (PAH) are believed tobeamong theprincipal causative agents for lungcancer in smokers, but no epidemiologic studies have evaluated the relationship of PAH uptake and metabolism to lung cancer. In this study, we quantified prediagnostic urinary levels of r-1,t-2,3,c-4-tetrahydroxy-1,2,3,4-tetrahydrophenanthrene (PheT), a validated biomarker of PAH uptake andmetabol...

Studies have used 8-hydroxydeoxyguanosine (8-OHdG) as a biomarker to detect systemic oxidative DNA damage associated with oxidative stress. However, studies on the association between exposure to tobacco smoking and urinary 8-OHdgG give inconsistent results. Limited studies have estimated the oxidative stress among office workers. This study assessed the association between urinary 8-OHdG and c...

This study examined urinary cotinine levels and self-reported smoking among pregnant women in Korea and the factors associated with smoking during pregnancy. The subjects were selected from pregnant women who visited 30 randomly sampled obstetric clinics and prenatal care hospitals in Korea in 2006. Smoking status was determined by self-reporting and urinary cotinine measurement. A total of 1,0...

Background & Aims: Exposure to cigarette smoke affects the health of mothers and infants. The aim of this study was to examine the effects of second-hand smoke exposure on breast milk and infant urinary cotinine during breastfeeding. Methods: This cohort study was conducted on 45 breastfeeding mothers and infants exposed to second-hand cigarette smoke (exposed group), and 40 breastfeeding mothe...

Abstract Background Although many indoor public places have implemented smoke-free regulations, private homes remained sources of tobacco smoke pollutants. This study examined differences in urinary cotinine concentrations the Korean non-smoking adult population between living smoking and homes, relationship with socio-demographic factors homes. Methods Samples from 2575 adults (≥19 years old) ...

OBJECTIVES Since the Health Promotion Act was introduced in Korea in 1995, anti-smoking policies and regulations have undergone numerous revisions, and non-smoking areas have gradually been expanded. The purpose of this study was to examine the impact of a partial legislative ban on adolescent exposure to secondhand smoke using objective urinary cotinine levels in a nationwide representative sa...

Purpose: Exposure to Environmental Tobacco Smoke (ETS) remains a worldwide public health problem. The purpose of this study was investigate the relationship between parents' smoking habits at home and children's exposure environmental tobacco smoke by measuring urinary cotinine levels urine cotinine/creatinine ratios in children.
 Materials Methods: This case-control typed analytical condu...

BACKGROUND Awareness of the negative effects of smoking on children's health prompted a decrease in the self-reporting of parental tobacco use in periodic surveys from most industrialized countries. Our aim is to assess changes between ETS exposure at the end of pregnancy and at 4 years of age determined by the parents' self-report and measurement of cotinine in age related biological matrices....

BACKGROUND Many Japanese believe that low-yield cigarettes are less hazardous than regular cigarettes, and many smokers consume low-yield cigarettes to reduce their risks from smoking. We evaluate the association between actual nicotine intake and brand nicotine yield, and the influence of nicotine dependence on this association. METHODS The study subjects included 458 Japanese male smokers, ...

OBJECTIVE Tobacco education is among the initiatives encouraged for health professionals to help them appreciate the significance of addressing tobacco use among their patients. In this pilot study, a nicotine biomarker (cotinine) study was introduced to an applied microbiology course required of all allied health students. Participants assessed their own smoking status in the previous 24 h usi...