Thymol is a phenolic monoterpene with colorless crystalline shapes or white powder spicy, caucasian and sweet taste. Its chemical structure characterized by hydroxyl group (-OH) attached to benzene ring. It provides for the hydroxylation of P-cymine along its carvacrol’s isomer. In this molecule different therapeutic properties have been registered in molecule, such as spasmolytic, anticancer, ...

Emergence of drug-resistant strains has demanded for alternative means of combating fungal infections. Oils of Carum copticum and Thymus vulgaris have long been used in ethnomedicine for ailments of various fungal infections. Since their activity has not been reported in particular against drug-resistant fungi, this study was aimed to evaluate the effects of oils of C. copticum and T. vulgaris ...

Background: Alternaria alternata (AA) is a fungus that has wide range of plant host and can cause diseases in humans and produces a number of mycotoxins. Exposure to high numbers of AA spores can trigger severe asthma exacerbations. Resistance to antifungal drug has been shown in this species. Trachyspermum copticum (Ajowan) is an annual herbaceous essential oil )EO) bearing plant . The ripenin...

Carum copticum L. commonly known as "Ajwain" is cultivated in many regions of the world including Iran and India, states of Gujarat and Rajasthan. Traditionally, C. copticum has been used in the past for various therapeutic effects including bloating, fatigue, diarrhea, abdominal tumors, abdominal pain, respiratory distress, and loss of appetite. It has other health benefits such as antifungal,...

BACKGROUND Several therapeutic effects including anti-asthma and dyspnea have been described for the seeds of Carum copticum. In previous studies the relaxant and anticholinergic (functional antagonism) effects, histamine H(1) inhibitory and beta(2) stimulatory effects of Carum copticum have been demonstrated on guinea pig tracheal chains. In the present study, the bronchodilatory effect of boi...

BACKGROUND Quorum sensing is a microbial cell-to-cell communication process. Quorum sensing bacteria produce and release extracellular messenger molecules called autoinducers. Gram-positive and Gram-negative, homoserine lactones, and oligopeptides are autoinducers used to communicate and regulate gene expression. OBJECTIVES The goal of this study was to assess the impact of subinhibitory conc...

The present work was designed to study the antioxidant activity and to identify the main active components of the essential oil of ajowan (Trachyspermum copticum) fruit. GC and GC-MS analyses of the essential oil showed the presence of eight compounds. The main constituents of the oil were thymol (43.7%), p-cymene (26.8%), and γ-terpinene (24.9%). The antioxidant and free radical scavenging act...