نتایج جستجو برای: toxin formation

تعداد نتایج: 575855  

Vacuolating cytotoxin (VacA) is one of the most important virulence factors of H. pylori (Hp), which isthe only toxic protein that is secreted from Hp cell into the culture supernatant. The effects of VacA oneukaryotic systems is the subject of many previous and on going research studies. Intracellular targetsfor this toxin include: late endosomal and lysosomal compartments, m...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه شهرکرد - دانشکده دامپزشکی 1394

استافیلوکوکوس ها اجرام باکتریایی، کروی و گرم مثبت به قطر 5/0 تا5/1 میکرون ، بی حرکت، فاقد اسپور، َهوازی و بی هوازی اختیاری و از خانواده میکروکوکاسه هستند . برخی از سویه های استافیلوکوکوس اورئوس فاکتورهای حدت متعددی شامل توکسین های سندروم شوک حرارتی (toxic shock syndrome toxin)، توکسین های اگزوفولیاتیو (exfoliative toxin) ،لوکوسیدین (lecukocidin) و .... را تولید و ترشح می کنند. مقاومت به آنتی بیو...

2016
Marcus V. Merfa Bárbara Niza Marco A. Takita Alessandra A. De Souza

Through the formation of persister cells, bacteria exhibit tolerance to multidrug and other environmental stresses without undergoing genetic changes. The toxin-antitoxin (TA) systems are involved in the formation of persister cells because they are able to induce cell dormancy. Among the TA systems, the MqsRA system has been observed to be highly induced in persister cells of Xylella fastidios...

Hossein Forghani, Hossein Zarei Jaliani, Mahin Jamshidi Makiani, Mina Boustanshenas, Seyed Mohsen Zahraei,

Background: Some resources have suggested that genetically inactivated pertussis toxoid (PTs) bear a more protective effect than chemically inactivated products. This study aimed to produce new version of PT, by cloning an inactive pertussis toxin S1 subunit (PTS1) in a fusion form with N-terminal half of the listeriolysin O (LLO) pore-forming toxin. Methods: Deposited pdb structure file of the...

Journal: :The Journal of Cell Biology 1983
S Kellie B Patel E J Pierce D R Critchley

We used cholera toxin, which binds exclusively and with a high affinity to the ganglioside GM1, as a probe to investigate the distribution of this glycolipid on the surface of mouse lymphocytes. When lymphocytes are incubated with cholera toxin (or its B subunit) and then sequentially with horse anti-toxin and FITC-swine anti-horse Ig at 37 degrees C, the cholera toxin-ganglioside GM1 complex i...

Journal: :Plant physiology 1984
A Kimber H Sze

The effects of purified Helminthosporium maydis T (HmT) toxin on active Ca(2+) transport into isolated mitochondria and microsomal vesicles were compared for a susceptible (T) and a resistant (N) strain of corn (Zea mays). ATP, malate, NADH, or succinate could drive (45)Ca(2+) transport into mitochondria of corn roots. Ca(2+) uptake was dependent on the proton electrochemical gradient generated...

Journal: :the iranian journal of pharmaceutical research 0
alireza tavakkoli school of pharmacy mashhad ali ahmadi school of pharmacy mashhad bibi marjan razavi targeted drug delivery research center, department of pharmacodynamy and toxicology, school of pharmacy, mashhad university of medical sciences, mashhad, hossein hosseinzadeh pharmaceutical research center, school of pharmacy, mashhad university of medical sciences, p. o. box 91775-1365, mashhad, i. r. iran,

nigella sativa (n. sativa), which belongs to the botanical family of ranunculaceae, is a widely used medicinal plant all over the world. n. sativa seeds and oil have been used in the treatment of different diseases. various studies on n. sativa have been carried out and a broad spectrum of its pharmacological actions have been established which include antioxidant, antidiabetic, anticancer, ant...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2007
Asparouh I Iliev Jasmin Roya Djannatian Roland Nau Timothy J Mitchell Fred S Wouters

The Streptococcus pneumoniae toxin pneumolysin belongs to the group of cholesterol-dependent cytolysins. It produces rapid cell lysis at higher concentrations or apoptosis at lower concentrations. In cell membranes, it forms prepores and pores. Here, we show that sublytic concentrations of pneumolysin produce rapid activation of Rho and Rac GTPases and formation of actin stress fibers, filopodi...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1996
K Sandvig O Garred B van Deurs

Cholera toxin is normally observed only in the Golgi apparatus and not in the endoplasmic reticulum (ER) although the enzymatically active A subunit of cholera toxin has a KDEL sequence. Here we demonstrate transport of horseradish peroxidase-labeled cholera toxin to the ER by electron microscopy in thapsigargin-treated A431 cells. Thapsigargin treatment strongly increased cholera toxin-induced...

2008
Yuichi Abe Sakae Kitada Osamu Kuge Michio Ohba Akio Ito

Parasporin-2, a new crystal protein from non-insecticidal Bacillus thuringiensis, exhibits strong cytocidal activity against various mammalian cells with divergent target specificity. The toxin binds to the surface of target cells and increases permeability of plasma membrane. Subcellular fractionation and immunoblot analysis of the toxin-treated cells revealed that the toxin bound to lipid raf...

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